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Gene Expression Data
Assay Details
Assay
Reference: J:316150 Li R, et al., A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons. Cell Res. 2012 May;22(5):859-72
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7448697
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-activated caspase 3
Detection system: Secondary antibody
Results
Specimen 5A Casp3 Neocortex CNS-ctr: embryonic day 15.5; Nbntm2Zqw/Nbntm2Zqw (more )
Structure Level Pattern Image Note
TS23: neocortex Ambiguous 5A caspase 3 Neocortex CNS-ctr Expression in control was not described.
Specimen 5A Casp3 Neocortex CNS-del: embryonic day 15.5; Nbntm2Zqw/Nbntm2Zqw, Tg(Nes-cre)1Wme/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: neocortex Absent 5A caspase 3 Neocortex CNS-del No cell death reported in cortex at E15.5
Specimen 5A Casp3 Medulla oblongata CNS-ctr: embryonic day 12.5; Nbntm2Zqw/Nbntm2Zqw (more )
Structure Level Pattern Image Note
TS20: medulla oblongata Ambiguous 5A caspase 3 Medulla oblongata CNS-ctr Expression in control was not described.
Specimen 5A Casp3 Medulla oblongata CNS-del: embryonic day 12.5; Nbntm2Zqw/Nbntm2Zqw, Tg(Nes-cre)1Wme/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: medulla oblongata Present 5A caspase 3 Medulla oblongata CNS-del Authors report expression in pyknotic cells with fragmented nuclei.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory