Gene Expression Data
Assay Details
Assay
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Reference:
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J:195901
Ehlen H, Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues. J Bone Miner Res. 2013;28(2):246-59
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7451013
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Gene symbol:
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Ano6
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Gene name:
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anoctamin 6
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Probe:
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Ano6 probe
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Probe preparation:
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Antisense labelled with P33 RNA
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Results
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Specimen
1A:
embryonic day 14.5
(more )
Specimen
1A:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS22: chondrocranium |
Present |
Regionally restricted |
1A
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Expression is in mineralizing tissues of intramembranous bone.
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TS22: craniocervical region bone |
Present |
Regionally restricted |
1A
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Expression is in mineralizing tissues of intramembranous bone.
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Specimen
1B:
embryonic day 16.5
(more )
Specimen
1B:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
|
Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS24: chondrocranium |
Present |
Regionally restricted |
1B
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Expression is in mineralizing tissues of intramembranous bone.
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TS24: facial bone |
Present |
Regionally restricted |
1B
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Expression is in mineralizing tissues of intramembranous bone.
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Specimen
1C:
embryonic day 14.5
(more )
Specimen
1C:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS22: bone |
|
Present |
Regionally restricted |
1C
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Expression is in mineralizing tissues of endochondral bone.
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TS22: rib cartilage condensation |
|
Present |
Regionally restricted |
1C
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Expression is in mineralizing tissues of endochondral bone.
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TS22: vertebra |
|
Present |
Regionally restricted |
1C
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Expression is in mineralizing tissues of endochondral bone.
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TS22: perichondrium |
osteoblast |
Present |
Regionally restricted |
1C
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Expression is in differentiating osteoblasts of the perichondrium/periosteum of endochondral bones.
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TS22: periosteum |
osteoblast |
Present |
Regionally restricted |
1C
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Expression is in differentiating osteoblasts of the perichondrium/periosteum of endochondral bones.
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Specimen
1D:
embryonic day 16.5
(more )
Specimen
1D:
(close )
Genetic Background:
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Not Specified
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Age:
|
embryonic day 16.5
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Sex:
|
Not Specified
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Type:
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section
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: bone |
Present |
Regionally restricted |
1D
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Expression is in mineralizing tissues of endochondral bone.
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TS24: long bone |
Present |
Regionally restricted |
1D
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Expression is in mineralizing tissues of endochondral bone.
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TS24: rib |
Present |
Regionally restricted |
1D
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Expression is in mineralizing tissues of endochondral bone.
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TS24: vertebra |
Present |
Regionally restricted |
1D
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Expression is in mineralizing tissues of endochondral bone.
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Specimen
1E:
embryonic day 16.5
(more )
Specimen
1E:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
|
Not Specified
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Type:
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section
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Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS24: perichondrium |
osteoblast |
Present |
Regionally restricted |
1E
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Expression is absent in regions of the perichondrium adjacent to proliferating chondrocytes.
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TS24: periosteum |
osteoblast |
Present |
Regionally restricted |
1E
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Expression is absent in regions of the perichondrium adjacent to proliferating chondrocytes.
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TS24: forelimb bone |
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Present |
Regionally restricted |
1E
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Expression is in the newly formed trabeculae and in the primary ossification centers.
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Specimen
1G:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Ihhtm1Amc/Ihhtm1Amc
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
1I:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx2tm1Kish/Runx2tm1Kish
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
1J:
(close )
Genetic Background:
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involves: 129S7/SvEvBrd
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Mutant Allele(s):
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Sp7tm1Crm/Sp7tm1Crm
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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