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Gene Expression Data
Assay Details
Assay
Reference: J:330602 Zhou T, et al., Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice. Nat Commun. 2022 Oct 24;13(1):6233
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7451199
Gene symbol: Aif1
Gene name: allograft inflammatory factor 1
Antibody: anti-Iba1 (019-19741)
Detection system: Secondary antibody coupled to Alexa Fluor
Assay notes: The authors reported using two Iba1 antibodies but did not specify which was used to obtain these data; it is possible MGI:6386249 was used.
Results
Specimen S9b - cortex microglia: postnatal; P2ry12em1(cre/ERT2)Peng/P2ry12+ (more )
Note: Double labeled: red - Aif1; green - P2ry12 reporter (assay MGI:7450957).
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex microglial cell Present S9b cortex
Specimen S9b - meningeal: postnatal; P2ry12em1(cre/ERT2)Peng/P2ry12+ (more )
Note: Double labeled: red - Aif1; green - P2ry12 reporter (assay MGI:7450957).
Structure Cell Type Level Pattern Image Note
TS28: brain meninges meningeal macrophage Present S9b meningeal
Specimen S9b - choroid plexus: postnatal; P2ry12em1(cre/ERT2)Peng/P2ry12+ (more )
Note: Double labeled: red - Aif1; green - P2ry12 reporter (assay MGI:7450957).
Structure Cell Type Level Pattern Image Note
TS28: choroid plexus choroid plexus macrophage Present S9b choroid plexus
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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