About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:146199 Barrionuevo F, et al., Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8. Dev Biol. 2009 Mar 15;327(2):301-12
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7464305
Gene symbol: Zbtb16
Gene name: zinc finger and BTB domain containing 16
Antibody: anti-PLZF (D-9) (sc-28319)
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: Fixation with 3.7% formaldehyde.
Results
Specimen 1Fa: postnatal month 5 (more )
Structure Level Pattern Image Note
TS28: germ cell of testis Present 1Fa Expression in spermatogonial stem cells in about 2/3rd of tubules.

Specimen 1Fb: postnatal month 5; Sox9tm1Gsr/Sox9tm1Gsr, Plekha5Tg(AMH-cre)1Flor/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: seminiferous tubule Absent 1Fb Expression absent from mutant tubules.

Specimen 7Cd: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: germ cell of testis Present Regionally restricted 7Cd Expression in spermatogonial stem cells at periphery of tubules.

Specimen 7Ce: postnatal day 12 (more )
Structure Level Pattern Image Note
TS28: germ cell of testis Present Regionally restricted 7Ce Expression in spermatogonial stem cells at periphery of tubules.

Specimen 7Cf: postnatal day 18 (more )
Structure Level Pattern Image Note
TS28: germ cell of testis Present Regionally restricted 7Cf Expression in spermatogonial stem cells at periphery of tubules.

Specimen 7Cj: postnatal day 6; Sox8tm1Weg/Sox8tm1Weg, Sox9tm1Gsr/Sox9tm1Gsr, Plekha5Tg(AMH-cre)1Flor/Plekha5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: seminiferous tubule Present Regionally restricted 7Cj Expresion at periphery and lumen of mutant tubules.

Specimen 7Ck: postnatal day 12; Sox8tm1Weg/Sox8tm1Weg, Sox9tm1Gsr/Sox9tm1Gsr, Plekha5Tg(AMH-cre)1Flor/Plekha5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: seminiferous tubule Present Regionally restricted 7Ck Expresion at periphery and lumen of mutant tubules.

Specimen 7Cl: postnatal day 18; Sox8tm1Weg/Sox8tm1Weg, Sox9tm1Gsr/Sox9tm1Gsr, Plekha5Tg(AMH-cre)1Flor/Plekha5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: seminiferous tubule Present Regionally restricted 7Cl Expression absent except for very few tubules, mainly located inside tubule.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
06/12/2024
MGI 6.13
The Jackson Laboratory