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Gene Expression Data
Assay Details
Assay
Reference: J:226036 Maddala R, et al., Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis. Dev Biol. 2015 Oct 1;406(1):74-91
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7464767
Gene symbol: Snai2
Gene name: snail family zinc finger 2
Antibody: SLUG antibody
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 8B E15.5 WT: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lens epithelium Ambiguous 8B E15.5 WT
TS23: lens fiber Ambiguous 8B E15.5 WT
Specimen 8B E15.5 cKO: embryonic day 15.5; Rap1atm1Morz/Rap1atm1Morz, Rap1btm1Morz/Rap1btm1Morz, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: lens epithelium Present 8B E15.5 cKO Increased expression compared with the control.
TS23: lens fiber Weak 8B E15.5 cKO Slightly increased expression compared with the control.
Specimen 8B E17.5 WT: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: lens epithelium Ambiguous 8B E17.5 WT
TS25: lens fiber Ambiguous 8B E17.5 WT
Specimen 8B E17.5 cKO: embryonic day 17.5; Rap1atm1Morz/Rap1atm1Morz, Rap1btm1Morz/Rap1btm1Morz, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: lens epithelium Present 8B E17.5 cKO Robustly increased expression compared with the control.
TS25: lens fiber Weak 8B E17.5 cKO Slightly increased expression compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory