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Gene Expression Data
Assay Details
Assay
Reference: J:271281 Bowles J, et al., Retinoic Acid Antagonizes Testis Development in Mice. Cell Rep. 2018 Jul 31;24(5):1330-1341
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7466639
Gene symbol: Amh
Gene name: anti-Mullerian hormone
Antibody: anti-AMH/MIS (C-20; sc-6886)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3A Wt AMH: embryonic day 13.5 (more )
Note: Double labeled: green - Amh; red - Ddx4 (assay MGI:7466615).
Structure Cell Type Level Pattern Image Note
TS21: Sertoli cell Sertoli cell Present 3A XY Wt left inset , 3A XY Wt left
TS21: testis Present Widespread 3A XY Wt left inset , 3A XY Wt left
Specimen 3A KO AMH: embryonic day 13.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd (more )
Note: Double labeled: green - Amh; red - Ddx4 (assay MGI:7466615).
Structure Cell Type Level Pattern Image Note
TS21: Sertoli cell Sertoli cell Present 3A XY KO left , 3A XY KO left inset
TS21: gonad Present Regionally restricted 3A XY KO left inset , 3A XY KO left In the mutant there is a lack of expressing cells at the anterior gonadal pole.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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