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Gene Expression Data
Assay Details
Assay
Reference: J:271281 Bowles J, et al., Retinoic Acid Antagonizes Testis Development in Mice. Cell Rep. 2018 Jul 31;24(5):1330-1341
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7466664
Gene symbol: Pax2
Gene name: paired box 2
Antibody: anti Pax2 Z-RX2 (71-6000)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen XY Wt: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nephric duct of male Present 4C XY Wt/het The Mullerian duct is ~ half the diameter of the Wolffian duct, reflecting Mullerian duct regression and Wolffian duct maturation.
TS22: paramesonephric duct of male Present 4C XY Wt/het The Mullerian duct is ~ half the diameter of the Wolffian duct, reflecting Mullerian duct regression and Wolffian duct maturation.
Specimen XY het: embryonic day 14.5; Cyp26b1tm1Hmd/Cyp26b1+ (more )
Structure Level Pattern Image Note
TS22: nephric duct of male Present 4C XY Wt/het The Mullerian duct is ~ half the diameter of the Wolffian duct, reflecting Mullerian duct regression and Wolffian duct maturation.
TS22: paramesonephric duct of male Present 4C XY Wt/het The Mullerian duct is ~ half the diameter of the Wolffian duct, reflecting Mullerian duct regression and Wolffian duct maturation.
Specimen XY KO: embryonic day 14.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd (more )
Structure Level Pattern Image Note
TS22: nephric duct Present 4C XY KO In the mutant the Mullerian duct is similar in thickness to the Wolffian duct.
TS22: paramesonephric duct Present 4C XY KO In the mutant the Mullerian duct is similar in thickness to the Wolffian duct.
Specimen XX Wt: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nephric duct of female Present 4C XX Wt/het The Mullerian duct is 50% wider than the diameter of the Wolffian duct.
TS22: paramesonephric duct of female Present 4C XX Wt/het The Mullerian duct is 50% wider than the diameter of the Wolffian duct.
Specimen XX het: embryonic day 14.5; Cyp26b1tm1Hmd/Cyp26b1+ (more )
Structure Level Pattern Image Note
TS22: nephric duct of female Present 4C XX Wt/het The Mullerian duct is 50% wider than the diameter of the Wolffian duct.
TS22: paramesonephric duct of female Present 4C XX Wt/het The Mullerian duct is 50% wider than the diameter of the Wolffian duct.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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