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Gene Expression Data
Assay Details
Assay
Reference: J:297164 Nie X, et al., mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. Dev Biol. 2020 Nov 1;467(1-2):77-87
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7467025
Gene symbol: Amelx
Gene name: amelogenin, X-linked
Antibody: Amelogenin (F-11): sc-365284
Detection system: Secondary antibody coupled to Alexa Fluor 546
Results
Specimen 2I: postnatal day 0; Mtortm1.2Koz/Mtor+ (more )
Structure Cell Type Level Pattern Image Note
TS27: molar enamel organ ameloblast Present 2I
Specimen 2J: postnatal day 0; Mtortm1.2Koz/Mtortm1.2Koz, Tg(KRT14-cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: molar enamel organ ameloblast Trace 2J Significantly reduced expression compared to controls.
Specimen 2V: postnatal day 0; Mtortm1.2Koz/Mtor+ (more )
Structure Cell Type Level Pattern Image Note
TS27: incisor enamel organ ameloblast Present 2V
Specimen 2W: postnatal day 0; Mtortm1.2Koz/Mtortm1.2Koz, Tg(KRT14-cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: incisor enamel organ ameloblast Trace 2W Significantly reduced expression compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory