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Gene Expression Data
Assay Details
Assay
Reference: J:256230 Shin SW, et al., Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice. Nat Commun. 2017 Nov 21;8(1):1643
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7482804
Gene symbol: Sqstm1
Gene name: sequestosome 1
Antibody: anti-SQSTM1/p62 (ab91526)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4a p62: embryonic day 0.5 (more )
Note: Double labeled: green - Sqstm1 (p62); red - phalloidin.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present Punctate 4a p62 , 4a p62 Merge Punctate expression in periphery of cytoplasm near plasma membrane.
Specimen 4b p62: embryonic day 0.5; Dppa3tm1Masu/Dppa3tm1Masu (more )
Note: Embryos resulting from mating of Dppa3 KO females with WT males. Double labeled: green - Sqstm1 (p62); red - phalloidin.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present Regionally restricted 4b p62 Merge , 4b p62 Expression abnormally aggregated in cytoplasm, colocalized with actin.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory