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Gene Expression Data
Assay Details
Assay
Reference: J:332246 Xie F, et al., N6-methyladenosine (m6A) RNA methylation mediated by methyltransferase complex subunit WTAP regulates amelogenesis. J Biol Chem. 2022 Dec;298(12):102715
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7490103
Gene symbol: Amelx
Gene name: amelogenin, X-linked
Antibody: anti-amelogenin
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3A: postnatal day 0.5; Wtaptm1c(EUCOMM)Hmgu/Wtaptm1c(EUCOMM)Hmgu (more )
Structure Level Pattern Image Note
TS27: inner enamel epithelium Present Regionally restricted 3A upper , 3A lower Expressed in the anterior end of labial side.
TS27: lower jaw incisor enamel organ Present Regionally restricted 3A upper , 3A lower Expressed in the anterior end of labial side.
Specimen 3E: postnatal day 0.5; Tg(KRT14-cre)1Amc/0, Wtaptm1c(EUCOMM)Hmgu/Wtaptm1c(EUCOMM)Hmgu (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: inner enamel epithelium Weak 3E lower , 3E upper Expression was significantly decreased in the mutant (quantified in 3I).
TS27: lower jaw incisor enamel organ Weak 3E lower , 3E upper Expression was significantly decreased in the mutant (quantified in 3I).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory