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Gene Expression Data
Assay Details
Assay
Reference: J:244948 Wang DY, et al., Endoplasmic reticulum resident protein 44 (ERp44) deficiency in mice and zebrafish leads to cardiac developmental and functional defects. J Am Heart Assoc. 2014 Oct 20;3(5):e001018
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7493443
Gene symbol: Erp44
Gene name: endoplasmic reticulum protein 44
Antibody: anti-ERp44
Results
Specimen 3A +/+: postnatal adult (more )
Structure Level Pattern Image Note
TS28: heart Present 3A +/+

Specimen 3A -/-: postnatal adult; Erp44Gt(XB599)Byg/Erp44Gt(XB599)Byg (more )
Structure Level Pattern Image Note
TS28: heart Absent 3A -/-

Specimen 4D ERp44 E13: embryonic day 13.0; Erp44Gt(XB599)Byg/Erp44+ (more )
Structure Level Pattern Image Note
TS21: heart Present Regionally restricted 4D ERp44 E13 Authors report a very specific expression pattern during maturation of heart.

Specimen 4D ERp44 P1: postnatal day 1; Erp44Gt(XB599)Byg/Erp44+ (more )
Structure Level Pattern Image Note
TS27: heart Present Regionally restricted 4D ERp44 P1 Authors report a very specific expression pattern during maturation of heart.

Specimen 4D ERp44 P7: postnatal day 7; Erp44Gt(XB599)Byg/Erp44+ (more )
Structure Level Pattern Image Note
TS28: heart Present Regionally restricted 4D ERp44 P7 Authors report a very specific expression pattern during maturation of heart.

Specimen 4D ERp44 12 wk: postnatal week 12; Erp44Gt(XB599)Byg/Erp44+ (more )
Structure Level Pattern Image Note
TS28: heart Present Regionally restricted 4D ERp44 12 w Authors report a very specific expression pattern during maturation of heart.

Specimen 4E ERp44: postnatal day 7; Erp44Gt(XB599)Byg/Erp44+ (more )
Note: Double labeled: green - Erp44 protein; red - Erp44 reporter (assay MGI:7493439).
Structure Level Pattern Image Note
TS28: visceral pericardium Strong 4E Merged , 4E ERp44 Higher expression in epicardium compared to myocardium.
TS28: cardiac muscle tissue Weak 4E Merged , 4E ERp44

Specimen Epicardium +/+ not shown: postnatal week 12 (more )
Structure Level Pattern Image Note
TS28: visceral pericardium Strong Expression in epicardium signicantly higher to myocardium

Specimen Epicardium +/- not shown: postnatal week 12; Erp44Gt(XB599)Byg/Erp44+ (more )
Structure Level Pattern Image Note
TS28: visceral pericardium Weak Expression in epicardium signficantly lower in heterozygote compared to wild type.

Specimen Myocardium +/+ not shown: postnatal week 12 (more )
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Weak

Specimen Myocardium +/- not shown: postnatal week 12; Erp44Gt(XB599)Byg/Erp44+ (more )
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Weak

Specimen 4G: embryonic day 13.0; Erp44Gt(XB599)Byg/Erp44+ (more )
Structure Level Pattern Image Note
TS21: heart Very strong 4G Very strong expression at E13.

Specimen 4H: embryonic day 13.0; Erp44Gt(XB599)Byg/Erp44+ (more )
Structure Level Pattern Image Note
TS21: heart Very strong 4H Very strong expression at E13.

Specimen 4I: postnatal week 3; Erp44Gt(XB599)Byg/Erp44+ (more )
Structure Level Pattern Image Note
TS28: heart Present Regionally restricted 4I High expression in outer epicardial region and epicardial/myocardial border.

Specimen 4J: postnatal adult; Erp44Gt(XB599)Byg/Erp44+ (more )
Note: Multi-labeled: green - Erp44; white - Pecam1 (assay MGI:7493445); red - phalloidin (F-actin); blue - Hoechst.
Structure Level Pattern Image Note
TS28: heart Present 4J

Specimen 4K ERp44: postnatal adult; Erp44Gt(XB599)Byg/Erp44+ (more )
Structure Level Pattern Image Note
TS28: heart Present Graded 4K ERp44 Graded expression in epicardium/myocardium region


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory