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Gene Expression Data
Assay Details
Assay
Reference: J:234197 Wong BH, et al., Mfsd2a Is a Transporter for the Essential omega-3 Fatty Acid Docosahexaenoic Acid (DHA) in Eye and Is Important for Photoreceptor Cell Development. J Biol Chem. 2016 May 13;291(20):10501-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7507602
Gene symbol: Ezr
Gene name: ezrin
Results
Specimen 1C WT Ezrin: postnatal day 14 (more )
Note: Double labeled: green - Ezr; red - Mfsd2a (assay MGI:7507598).
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present Regionally restricted 1C WT Ezrin , 1C WT Merge Expression in apical and basolateral membranes in retina pigmented epithelium.
Specimen 1C KO Ezrin: postnatal day 14; Mfsd2atm1Dls/Mfsd2atm1Dls (more )
Note: Double labeled: green - Ezr; red - Mfsd2a (assay MGI:7507598).
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present Regionally restricted 1C KO Merge , 1C KO Ezrin Expression in apical and basolateral membranes in retina pigmented epithelium.
Specimen 5G P13 WT: postnatal day 13 (more )
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present Regionally restricted 5G P13 WT Expression in hair-like apical villi.
Specimen 5G P13 KO: postnatal day 13; Mfsd2atm1Dls/Mfsd2atm1Dls (more )
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present Regionally restricted 5G P13 KO Villi appear disorganized.
Specimen 5G 5mth WT: postnatal month 5 (more )
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present Regionally restricted 5G 5mth WT Expression in hair-like apical villi.
Specimen 5G 5mth KO: postnatal month 5; Mfsd2atm1c(KOMP)Wtsi/Mfsd2atm1c(KOMP)Wtsi, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present Regionally restricted 5G 5mth KO Villi appear collapsed onto itself.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory