Lgr4 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:212415 Kinzel B, et al., Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90
Assay type:	RNA in situ
MGI Accession ID:	MGI:7509111
Gene symbol:	Lgr4
Gene name:	leucine-rich repeat-containing G protein-coupled receptor 4

Probe:	Lgr4 cDNA
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

2A bottom ©

2A top ©

Specimen 2A: embryonic day 16.5; Lgr5^{tm1.1(cre/ERT2)Npa}/Lgr5⁺ (more

)

Structure	Level	Pattern	Image	Note
TS24: intestine epithelium	Present		2A bottom , 2A top

4A ©

Specimen 4A: embryonic day 16.5; Lgr5^{tm1.1(cre/ERT2)Npa}/Lgr5⁺ (more

)

Structure	Level	Pattern	Image	Note
TS24: epidermis basal layer	Present		4A
TS24: hair follicle	Present		4A

5A left ©

5A right ©

Specimen 5A: embryonic day 16.5; Lgr5^{tm1.1(cre/ERT2)Npa}/Lgr5⁺ (more

)

Structure	Level	Pattern	Image	Note
TS24: Bowman's capsule of maturing renal corpuscle	Present		5A right , 5A left
TS24: renal tubule	Present	Regionally restricted	5A left , 5A right	Expression is in the tubular epithelium.

S2_Lgr4 wt ©

Specimen S2 wt: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: intestine epithelium	Present		S2_Lgr4 wt

S2_Lgr4 Lgr5KO ©

Specimen S2 Lgr5KO: embryonic day 16.5; Lgr5^{tm1.1(cre/ERT2)Npa}/Lgr5^{tm1.1(cre/ERT2)Npa} (more

)

Structure	Level	Pattern	Image	Note
TS24: intestine epithelium	Present		S2_Lgr4 Lgr5KO

S2_Lgr4 Lgr4KO ©

Specimen S2 Lgr4KO: embryonic day 16.5; Lgr4^{tm1.1(cre/ERT2)Npa}/Lgr4^{tm1.1(cre/ERT2)Npa} (more

)

Structure	Level	Pattern	Image	Note
TS24: intestine	Absent		S2_Lgr4 Lgr4KO

S2_Lgr4 Lgr4/5dKO ©

Specimen S2 Lgr4/5dKO: embryonic day 16.5; Lgr4^{tm1.1(cre/ERT2)Npa}/Lgr4^{tm1.1(cre/ERT2)Npa}, Lgr5^{tm1.1(cre/ERT2)Npa}/Lgr5^{tm1.1(cre/ERT2)Npa} (more

)

Structure	Level	Pattern	Image	Note
TS24: intestine	Absent		S2_Lgr4 Lgr4/5dKO

S3_Lgr4 wt ©

Specimen S3 wt: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: epidermis basal layer	Present		S3_Lgr4 wt
TS24: hair follicle	Present		S3_Lgr4 wt

S3_Lgr4 Lgr5KO ©

Specimen S3 Lgr5KO: embryonic day 16.5; Lgr5^{tm1.1(cre/ERT2)Npa}/Lgr5^{tm1.1(cre/ERT2)Npa} (more

)

Structure	Level	Pattern	Image	Note
TS24: epidermis basal layer	Present		S3_Lgr4 Lgr5KO
TS24: hair follicle	Present		S3_Lgr4 Lgr5KO

S3_Lgr4 Lgr4KO ©

Specimen S3 Lgr4KO: embryonic day 16.5; Lgr4^{tm1.1(cre/ERT2)Npa}/Lgr4^{tm1.1(cre/ERT2)Npa} (more

)

Structure	Level	Pattern	Image	Note
TS24: epidermis basal layer	Absent		S3_Lgr4 Lgr4KO
TS24: hair follicle	Absent		S3_Lgr4 Lgr4KO

Specimen S3 Lgr4/5dKO: embryonic day 16.5; Lgr4^{tm1.1(cre/ERT2)Npa}/Lgr4^{tm1.1(cre/ERT2)Npa}, Lgr5^{tm1.1(cre/ERT2)Npa}/Lgr5^{tm1.1(cre/ERT2)Npa} (more

)

Structure	Level	Pattern	Image	Note
TS24: epidermis basal layer	Absent		S3_Lgr4 Lgr4/5dKO
TS24: hair follicle	Absent		S3_Lgr4 Lgr4/5dKO

S4_Lgr4 wt ©

Specimen S4 wt: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: Bowman's capsule of maturing renal corpuscle	Present		S4_Lgr4 wt
TS24: renal tubule	Present		S4_Lgr4 wt

Specimen S4 Lgr5KO: embryonic day 16.5; Lgr5^{tm1.1(cre/ERT2)Npa}/Lgr5^{tm1.1(cre/ERT2)Npa} (more

)

Structure	Level	Pattern	Image	Note
TS24: Bowman's capsule of maturing renal corpuscle	Present		S4_Lgr4 Lgr5KO
TS24: renal tubule	Present		S4_Lgr4 Lgr5KO

Specimen S4 Lgr4KO: embryonic day 16.5; Lgr4^{tm1.1(cre/ERT2)Npa}/Lgr4^{tm1.1(cre/ERT2)Npa} (more

)

Structure	Level	Pattern	Image	Note
TS24: metanephros	Absent		S4_Lgr4 Lgr4KO

Specimen S4 Lgr4/5dKO: embryonic day 16.5; Lgr4^{tm1.1(cre/ERT2)Npa}/Lgr4^{tm1.1(cre/ERT2)Npa}, Lgr5^{tm1.1(cre/ERT2)Npa}/Lgr5^{tm1.1(cre/ERT2)Npa} (more

)

Structure	Level	Pattern	Image	Note
TS24: metanephros	Absent		S4_Lgr4 Lgr4/5dKO

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