Gene Expression Data
Assay Details
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Assay
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Reference:
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J:321845
Bernhardt N, et al., Hop Mice Display Synchronous Hindlimb Locomotion and a Ventrally Fused Lumbar Spinal Cord Caused by a Point Mutation in Ttc26. eNeuro. 2022 Mar-Apr;9(2):ENEURO.0518-21.2022
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7509797
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Gene symbol:
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Slc18a3
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Gene name:
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solute carrier family 18 (vesicular monoamine), member 3
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Antibody:
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anti-VAChT
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Assay notes:
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Two Rbfox3 antibodies were described, but the one used in this assay was not detailed. Anti-NeuN MGI:7509750 may have been used in this assay.
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Results
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Specimen
7I:
embryonic day 16.5
(more  )
Specimen
7I:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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optical section
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Embedding:
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Cryosection
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Specimen
7J:
(close )
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Genetic Background:
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involves: C57BL/6J
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Mutant Allele(s):
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Ift56em1Kldr/Ift56em1Kldr
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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optical section
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS24: spinal cord lumbar region |
spinal cord motor neuron |
Present |
Regionally restricted |
7J
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Expression in two distinct populations of motor neurons on each side of midline, similar to controls.
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Specimen
7I':
embryonic day 16.5
(more )
Specimen
7I':
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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optical section
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS24: spinal cord |
cholinergic neuron |
Present |
Regionally restricted |
7I'
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Expression in central canal cholinergic cells normally separated by midline.
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Specimen
7J':
(close )
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Genetic Background:
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involves: C57BL/6J
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Mutant Allele(s):
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Ift56em1Kldr/Ift56em1Kldr
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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optical section
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS24: spinal cord |
cholinergic neuron |
Present |
Regionally restricted |
7J'
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Expression in cholinergic cells distributed closer to and even on midline.
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Analysis Tools
