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Gene Expression Data
Assay Details
Assay
Reference: J:228828 Hamazaki J, et al., Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis. PLoS Genet. 2015 Jul;11(7):e1005401
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7511440
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki-67 (SP6; MA5-14520, RM-9106)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 7B 2w Control: postnatal week 2 (more )
Structure Level Pattern Image Note
TS28: liver Present 7B Control 2w

Specimen 7B 2w DKO: postnatal week 2; Adrm1tm1Smta/Adrm1tm1Smta, Psmd4tm2.1Smta/Psmd4tm2.1Smta, Speer6-ps1Tg(Alb-cre)21Mgn/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: liver hepatocyte Present 7B DKO 2w

Specimen 7B 8w Control: postnatal week 8 (more )
Structure Level Pattern Image Note
TS28: liver Trace 7B Control 8w

Specimen 7B 8w DKO: postnatal week 8; Adrm1tm1Smta/Adrm1tm1Smta, Psmd4tm2.1Smta/Psmd4tm2.1Smta, Speer6-ps1Tg(Alb-cre)21Mgn/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: liver hepatocyte Strong 7B DKO 8w Hepatocyte proliferation in DKO mice, especially at 8 weeks of age.

Specimen 7B 5M Control: postnatal month 5 (more )
Structure Level Pattern Image Note
TS28: liver Weak 7B Control 5M

Specimen 7B 5M DKO: postnatal month 5; Adrm1tm1Smta/Adrm1tm1Smta, Psmd4tm2.1Smta/Psmd4tm2.1Smta, Speer6-ps1Tg(Alb-cre)21Mgn/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: liver hepatocyte Present 7B DKO 5M Confirmed hepatocyte proliferation in DKO mice.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory