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Gene Expression Data
Assay Details
Assay
Reference: J:198483 Finelli MJ, et al., Differential phosphorylation of Smad1 integrates BMP and neurotrophin pathways through Erk/Dusp in axon development. Cell Rep. 2013 May 30;3(5):1592-606
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7529728
Gene symbol: Ntrk1
Gene name: neurotrophic tyrosine kinase, receptor, type 1
Antibody: anti-TrkA
Results
Specimen 3E TrkA Control: postnatal day 1; Smad1tm1Abr/Smad1+, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: thoracic dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 3E TrkA Control Expression in differentiated sensory neurons.
Specimen 3E TrkA cKO-Nes: postnatal day 1; Smad1tm1Abr/Smad1tm1.1Abr, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: thoracic dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 3E TrkA cKO-Nes Total number of expressing-neurons similar to control.
Specimen S6E TrkA +/+: postnatal day 1 (more )
Structure Cell Type Level Pattern Image Note
TS27: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted S6E TrkA +/+
Specimen S6E TrkA L/L: postnatal day 1; Smad1tm2Sor/Smad1tm2Sor (more )
Structure Cell Type Level Pattern Image Note
TS27: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted S6E TrkA L/L No significant difference in percentage of differentiated neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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