Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:281166 Zhang X, et al., Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis. Nat Commun. 2019 Sep 13;10(1):4158
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7531229
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:

Results

1e +/+ CC3 ©

1e +/+ inset ©

1e +/+ merge ©

Specimen 1e WT: embryonic day 12.5 (more

)
Note: Double labeled: red - Casp3; green - Cdh5 (assay MGI:7531218).

Structure	Level	Pattern	Image	Note
TS20: yolk sac blood vessel	Absent		1e +/+ merge , 1e +/+ inset , 1e +/+ CC3

Specimen 1e K376R/K376R: embryonic day 12.5; Ripk1^em3Hbz/Ripk1^em3Hbz (more

)
Note: Double labeled: red - Casp3; green - Cdh5 (assay MGI:7531218).

Structure	Level	Pattern	Image	Note
TS20: yolk sac blood vessel	Present		1e K376R/K376R merge , 1e K376R/K376R CC3 , 1e K376R/K376R inset	Coexpressed with Cdh5.
TS20: yolk sac	Present		1e K376R/K376R CC3 , 1e K376R/K376R merge , 1e K376R/K376R inset

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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