About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:333559 Rupani DN, et al., Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling. Development. 2023 Jan 15;150(2):dev201097
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7539129
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Antibody: anti-Sox9 (D8G8H) (82630)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 2I Control: embryonic day 18.5; Adartm1Knk/?, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Ptf1a+/? (more )
Note: Triple labeled: green - Sox9; red - Amy (assay MGI:7539125); blue - hematoxylin. Control is either non-Cre-expressing OR Adar1 heterozygous litter mate.
Structure Cell Type Level Pattern Image Note
TS26: pancreatic duct pancreatic ductal cell Present 2I Control inset , 2I Control
Specimen 2I CYA: embryonic day 18.5; Adartm1Knk/Adartm1Knk, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Ptf1atm1.1(cre)Cvw/Ptf1a+ (more )
Note: Conditional mutant. Triple labeled: green - Sox9; red - Amy (assay MGI:7539125); blue - hematoxylin.
Structure Level Pattern Image Note
TS26: pancreas Present Regionally restricted 2I CYA inset , 2I CYA Increased number of cells co-expressing Sox9 and Amy.
Specimen 2J Control: postnatal day 21; Adartm1Knk/?, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Ptf1a+/? (more )
Note: Multi-labeled: green - Sox9; red - Amy (assay MGI:7539125); white - Krt19 (assay MGI:7539127); blue - hematoxylin. Control is either non-Cre-expressing OR Adar1 heterozygous litter mate.
Structure Cell Type Level Pattern Image Note
TS28: pancreatic duct pancreatic ductal cell Present 2J Control inset , 2J Control
Specimen 2J CYA: postnatal day 21; Adartm1Knk/Adartm1Knk, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Ptf1atm1.1(cre)Cvw/Ptf1a+ (more )
Note: Conditional mutant. Multi-labeled: green - Sox9; red - Amy (assay MGI:7539125); white - Krt19 (assay MGI:7539127); blue - hematoxylin.
Structure Level Pattern Image Note
TS28: pancreas Present Regionally restricted 2J CYA , 2J CYA inset Increased number of cells co-expressing Sox9 and Amy.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory