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Gene Expression Data
Assay Details
Assay
Reference: J:205196 Shetty AS, et al., Lhx2 regulates a cortex-specific mechanism for barrel formation. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):E4913-21
Assay type: RNA in situ
MGI Accession ID: MGI:7543273
Gene symbol: Gap43
Gene name: growth associated protein 43
Probe: Gap43 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3D: postnatal day 5-7 (more )
Structure Level Pattern Image Note
TS28: barrel cortex Present Regionally restricted 3D Expression was specifically excluded from the barrel core and was expressed in the cellular septae in between them.

Specimen 3H: postnatal day 5-7; Emx1tm1(cre)Yql/Emx1+, Lhx2tm1Monu/Lhx2tm1Dra (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: neocortex Present 3H Segregation in the controls was not seen.

Specimen 7F: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: barrel cortex Present Regionally restricted 7F Expression revealed barrel walls with unstained barrel cores.

Specimen 7G: postnatal day 7; Emx1tm1(cre)Yql/Emx1+, Pax6Sey/Pax6tm2Pgr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: barrel cortex Present Regionally restricted 7G A reduced barrel field was seen which displayed expression in barrel walls.

Specimen 7H: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: barrel cortex Present Regionally restricted 7H Expression revealed barrel walls with unstained barrel cores.

Specimen 7I: postnatal day 7; Emx1tm1(cre)Yql/Emx1+, Pax6Sey/Pax6tm2Pgr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: barrel cortex Present Regionally restricted 7I A reduced barrel field was seen which displayed expression in barrel walls.

Specimen 7J: postnatal day 7; Emx1tm1(cre)Yql/Emx1+, Lhx2tm1Monu/Lhx2tm1Dra (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: neocortex region Present 7J But there was a complete absence of barrel-like cytoarchitecture.

Specimen 7K: postnatal day 7; Emx1tm1(cre)Yql/Emx1+, Lhx2tm1Dra/Lhx2tm1Monu, Pax6Sey/Pax6tm2Pgr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: neocortex region Present 7K But there was a complete absence of barrel-like cytoarchitecture.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory