Gene Expression Data
Assay Details
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Assay
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Reference:
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J:122792
Jacobs FM, et al., Retinoic acid counteracts developmental defects in the substantia nigra caused by Pitx3 deficiency. Development. 2007 Jul;134(14):2673-84
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7571189
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Gene symbol:
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Aldh1a1
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Gene name:
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aldehyde dehydrogenase family 1, subfamily A1
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Probe:
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Ahd2 probe
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Probe preparation:
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labelled with P33
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Visualized with:
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Autoradiography
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Results
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Specimen
1AB:
postnatal adult
(more  )
Specimen
1AB:
(close  )
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Genetic Background:
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involves: C57BL/6
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: substantia nigra pars compacta |
Strong |
Regionally restricted |
1AB
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High levels of expression in cells located in the substantia nigra compacta. No expression in medial part.
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Specimen
1AD:
postnatal adult
(more )
Specimen
1AD:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: substantia nigra pars compacta |
Strong |
Regionally restricted |
1AD
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High levels of expression in cells located in the substantia nigra compacta. No expression in medial part.
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Specimen
1AF:
postnatal adult
(more )
Specimen
1AF:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: ventral tegmental area |
Present |
Regionally restricted |
1AF
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Expression in ventral tegmental area, predominantly in ventral and lateral parts, and in some scattered cells located more dorsally. No expression in dorso-medial part.
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Specimen
1AH:
postnatal adult
(more )
Specimen
1AH:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: ventral tegmental area |
Present |
Regionally restricted |
1AH
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Expression in ventral tegmental area, predominantly in ventral and lateral parts, and in some scattered cells located more dorsally. No expression in dorso-medial part.
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Specimen
1AJ:
postnatal adult
(more )
Specimen
1AJ:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: ventral tegmental area |
Present |
Regionally restricted |
1AJ
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Expression in ventral tegmental area, predominantly in ventral and lateral parts, and in some scattered cells located more dorsally. No expression in dorso-medial part.
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Specimen
1AL:
postnatal adult
(more )
Specimen
1AL:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: ventral tegmental area |
Present |
Regionally restricted |
1AL
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Expression in ventral tegmental area, predominantly in ventral and lateral parts, and in some scattered cells located more dorsally. No expression in dorso-medial part.
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Specimen
2 Ahd2 Lateral:
embryonic day 13.5
(more )
Specimen
2 Ahd2 Lateral:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: midbrain |
Present |
Regionally restricted |
2_Ahd2 Lateral
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Expression lateral part of meso-diencephalic dopaminergic (mdDA) area containing neurons in presumptive substantial nigra compacta and ventral tergmental area.
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Specimen
2 Ahd2 (2nd row):
embryonic day 13.5
(more )
Specimen
2 Ahd2 (2nd row):
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: midbrain |
Present |
Regionally restricted |
2_Ahd2 (2nd row)
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Expression lateral part of meso-diencephalic dopaminergic (mdDA) area containing neurons in presumptive substantial nigra compacta and ventral tergmental area.
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Specimen
2 Ahd2 (3rd row):
embryonic day 13.5
(more )
Specimen
2 Ahd2 (3rd row):
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: midbrain |
Present |
Regionally restricted |
2_Ahd2 (3rd row)
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Expression lateral part of meso-diencephalic dopaminergic (mdDA) area containing neurons in presumptive substantial nigra compacta and ventral tergmental area.
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Specimen
2 Ahd2 Medial:
embryonic day 13.5
(more )
Specimen
2 Ahd2 Medial:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: midbrain |
Present |
Regionally restricted |
2_Ahd2 Medial
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Expression lateral part of meso-diencephalic dopaminergic (mdDA) area containing neurons in presumptive substantial nigra compacta and ventral tergmental area.
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Specimen
3AB:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Pitx3ak/Pitx3ak
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: substantia nigra pars compacta |
Absent |
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3AB
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Expression completely absent from rostral part of meso-diencephalic dopaminergic (mdDA) area, which includes the substantia nigra compacta.
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Specimen
3AD:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Pitx3ak/Pitx3ak
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: substantia nigra pars compacta |
Absent |
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3AD
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Expression completely absent from rostral part of meso-diencephalic dopaminergic (mdDA) area, which includes the substantia nigra compacta.
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Specimen
3AF:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Pitx3ak/Pitx3ak
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: ventral tegmental area |
Weak |
Regionally restricted |
3AF
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Expression completely absent from rostral part of meso-diencephalic dopaminergic (mdDA) area, which includes the lateral part of the ventral tegmental area. Expression in some neurons in caudal part of mdDA area.
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Specimen
3B Ahd2 L:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Pitx3ak/Pitx3ak
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: midbrain |
Absent |
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3B Ahd2 L
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Expression completely lost in lateral part of meso-diencephalic dopaminergic (mdDA) area.
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Specimen
3B Ahd2 (2nd row):
embryonic day 13.5; Pitx3ak/ Pitx3ak
(more )
Specimen
3B Ahd2 (2nd row):
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Pitx3ak/Pitx3ak
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: midbrain |
Absent |
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3B Ahd2 (2nd row)
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Expression completely lost in lateral part of meso-diencephalic dopaminergic (mdDA) area.
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Specimen
3B Ahd2 M:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Pitx3ak/Pitx3ak
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: midbrain |
Absent |
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3B Ahd2 M
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Expression completely lost in lateral part of meso-diencephalic dopaminergic (mdDA) area.
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Specimen
4B Ahd2 (upper):
postnatal adult
(more )
Specimen
4B Ahd2 (upper):
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
4B Ahd2 (lower):
postnatal adult; Pitx3ak/Pitx3 +
(more )
Specimen
4B Ahd2 (lower):
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Pitx3ak/Pitx3+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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