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Gene Expression Data
Assay Details
Assay
Reference: J:129202 Dunty WC Jr, et al., Wnt3a/beta-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation. Development. 2008 Jan;135(1):85-94
Assay type: RNA in situ
MGI Accession ID: MGI:7574674
Gene symbol: Uncx
Gene name: UNC homeobox
Probe: Uncx4.1 cDNA1
Probe preparation: Antisense RNA
Results
Specimen 2Q: embryonic day 8.5 (more )
Note: Double labeled: orange - Uncx; purple - Hes7 (assay MGI:7574673).
Structure Level Pattern Image Note
TS13: somite Present 2Q
Specimen 2R: embryonic day 8.5; Ctnnb1tm2Kem/Ctnnb1tm2Kem, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant. Double labeled: orange - Uncx; purple - Hes7 (assay MGI:7574673).
Structure Level Pattern Image Note
TS13: somite Ambiguous 2R It appeared as absent in this color, higher contrast chromogens later revealed expression.
Specimen 2S: embryonic day 8.5; Ctnnb1tm1Mmt/Ctnnb1+, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant. Double labeled: orange - Uncx; purple - Hes7 (assay MGI:7574673).
Structure Level Pattern Image Note
TS13: somite Present 2S
Specimen 3G: embryonic day 8.0 (more )
Note: 5-7 somites. Double labeled: orange - Uncx; purple - Tbx18 (assay MGI:7574747).
Structure Level Pattern Image Note
TS12: somite Present 3G
Specimen 3H: embryonic day 8.0; Wnt3atm1Amc/Wnt3atm1Amc (more )
Note: 5-7 somites. Double labeled: orange - Uncx; purple - Tbx18 (assay MGI:7574747).
Structure Level Pattern Image Note
TS12: somite Present 3H Segment polarity was well preserved in the anterior Wnt3a-/- somites.
Specimen 3I: embryonic day 8.0; Ctnnb1tm2Kem/Ctnnb1tm2Kem, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant. 5-7 somites. Double labeled: orange - Uncx; purple - Tbx18 (assay MGI:7574747).
Structure Level Pattern Image Note
TS12: somite Present Regionally restricted 3I Segment polarity was aberrant and less well defined in the anterior LOF somites. Interspersed, fuzzy stripes were still detected posteriorly.
Specimen 3J: embryonic day 8.0; Ctnnb1tm1Mmt/Ctnnb1+, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant. 5-7 somites. Double labeled: orange - Uncx; purple - Tbx18 (assay MGI:7574747).
Structure Level Pattern Image Note
TS12: somite Present Regionally restricted 3J The caudal limit of the expression domain was shifted anteriorly in the GOF mutant. Expressed as two distinct stripes anteriorly, but was fused and disorganized posteriorly.
Specimen 3K/O: embryonic day 8.5 (more )
Note: 10 somites. Double labeled: orange - Uncx; purple - Mesp2 (assay MGI:7574751).
Structure Level Pattern Image Note
TS13: somite Present 3O , 3K
Specimen 3L/P: embryonic day 8.5; Wnt3atm1Amc/Wnt3atm1Amc (more )
Note: 10 somites. Double labeled: orange - Uncx; purple - Mesp2 (assay MGI:7574751).
Structure Level Pattern Image Note
TS13: somite Present 3P , 3L
Specimen 3M/Q: embryonic day 8.5; Ctnnb1tm1Mmt/Ctnnb1+, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant. 10 somites. Double labeled: orange - Uncx; purple - Mesp2 (assay MGI:7574751).
Structure Level Pattern Image Note
TS13: somite Present 3M , 3Q
Specimen 3N/R: embryonic day 8.5; Ctnnb1tm1Mmt/Ctnnb1+, Tg(T-cre)1Lwd/0, Wnt3atm1Amc/Wnt3atm1Amc (more )
Note: Conditional mutant. 10 somites. Double labeled: orange - Uncx; purple - Mesp2 (assay MGI:7574751).
Structure Level Pattern Image Note
TS13: somite Present 3R , 3N
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory