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Gene Expression Data
Assay Details
Assay
Reference: J:190564 Tavares AL, et al., Ectodermal-derived Endothelin1 is required for patterning the distal and intermediate domains of the mouse mandibular arch. Dev Biol. 2012 Nov 1;371(1):47-56
Assay type: RNA in situ
MGI Accession ID: MGI:7580430
Gene symbol: Dlx3
Gene name: distal-less homeobox 3
Probe: Dlx3 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5B: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mesenchyme Present Regionally restricted 5B Expression in proximo-caudal mesenchyme of mandibular arch.
TS17: 1st branchial arch ectoderm Present Regionally restricted 5B Expression in distal arch ectoderm.
Specimen 5G: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch ectoderm Absent 5G Expression almost completely lost in first pharyngeal arch mesenchyme and overlying ectoderm
TS17: 1st branchial arch mesenchyme Absent 5G Expression almost completely lost in first pharyngeal arch mesenchyme and overlying ectoderm
TS17: 2nd branchial arch Weak 5G Expression reduced in second pharyngeal arch.
Specimen 5L: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa, Tg(Tcfap2a-cre)1Will/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch Present 5L Expression unaffected compared to control.
Specimen 5Q: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa, Myf5tm3(cre)Sor/Myf5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch Present 5Q Expression unaffected compared to control.
Specimen 6A: embryonic day 9.5; Edn1tm1Ywa/Edn1tm1Ywa (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch Present 6A
Specimen 6B: embryonic day 9.5; Edn1tm1Ywa/Edn1tm1Ywa, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 1st branchial arch Trace 6B Expression almost completely absent in first arch.
Specimen 7G: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mesenchyme Present Regionally restricted 7G Expression in proximo-caudal mesenchyme of mandibular arch.
TS17: 1st branchial arch ectoderm Present Regionally restricted 7G Expression in distal arch ectoderm.
Specimen 7H: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch mesenchyme Absent 7H Expression absent in mandibular arch mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory