About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:190564 Tavares AL, et al., Ectodermal-derived Endothelin1 is required for patterning the distal and intermediate domains of the mouse mandibular arch. Dev Biol. 2012 Nov 1;371(1):47-56
Assay type: RNA in situ
MGI Accession ID: MGI:7580433
Gene symbol: Dlx5
Gene name: distal-less homeobox 5
Probe: Dlx5 probe
Probe preparation: Antisense labelled with fluorescein RNA
Visualized with: Alkaline phosphatase
Results
Specimen 7E: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa (more )
Note: Double labeled: magenta - Dlx5; blue - Nkx3-2 (assay MGI:7580436).
Structure Level Pattern Image Note
TS17: 1st branchial arch Present 7E
Specimen 7F: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant. Double labeled: magenta - Dlx5; blue - Nkx3-2 (assay MGI:7580436).
Structure Level Pattern Image Note
TS17: 1st branchial arch mesenchyme Present Regionally restricted 7F Residual mesenchyme expression confined to domain in which Dlx5 is absent.
Specimen 8E: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa (more )
Note: Double labeled: magenta - Dlx5; blue - Nkx3-2 (assay MGI:7580436).
Structure Level Pattern Image Note
TS17: 1st branchial arch mesenchyme Present Regionally restricted 8E Mesenchymal expression overlaps with that of Nkx3.2.
Specimen 8F: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa, Tg(Tcfap2a-cre)1Will/0 (more )
Note: Conditional mutant. Double labeled: magenta - Dlx5; blue - Nkx3-2 (assay MGI:7580436).
Structure Level Pattern Image Note
TS17: 1st branchial arch mesenchyme Present Regionally restricted 8F Expression lost in same central arch domain as for Nkx3.2.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory