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Gene Expression Data
Assay Details
Assay
Reference: J:205662 Takeuchi JK, et al., Chromatin remodelling complex dosage modulates transcription factor function in heart development. Nat Commun. 2011;2:187
Assay type: RNA in situ
MGI Accession ID: MGI:7611692
Gene symbol: Nppa
Gene name: natriuretic peptide type A
Probe: Nppa probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1d WT: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: primitive ventricle Present 1d Nppa WT
Specimen 1d cKO: embryonic day 9.5; Smarca4tm1.2Pcn/Smarca4tm1.2Pcn, Tg(Nkx2-5-cre)9Eno/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: primitive ventricle Weak 1d Nppa cKO Reduced expression compared with the wild-type.
Specimen 5a WT: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: primitive ventricle Present 5a Nppa WT
Specimen 5a Brg1+/-: embryonic day 9.5; Smarca4tm1.1Pcn/Smarca4+ (more )
Structure Level Pattern Image Note
TS15: primitive ventricle Present 5a Nppa Brg1+/- Similar as in the wild-type.
Specimen 5a Tbx5del/+: embryonic day 9.5; Tbx5tm1.1Jse/Tbx5+ (more )
Structure Level Pattern Image Note
TS15: primitive ventricle Present 5a Nppa Tbx5 del/+ Slightly reduced expression compared with the wild-type.
Specimen 5a Tbx5del/+;Brg1+/-: embryonic day 9.5; Smarca4tm1.1Pcn/Smarca4+, Tbx5tm1.1Jse/Tbx5+ (more )
Structure Level Pattern Image Note
TS15: primitive ventricle Absent 5a Nppa Tbx5 del/+;Brg1+/-
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory