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Gene Expression Data
Assay Details
Assay
Reference: J:331053 Chandrasekaran P, et al., CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth. Development. 2022 Nov 1;149(21):dev200909
Assay type: RNA in situ
MGI Accession ID: MGI:7616708
Gene symbol: Ackr3
Gene name: atypical chemokine receptor 3
Probe: Mm-Ackr3 (482561)
Probe preparation: Antisense
Visualized with: Fluorescence
Results
Specimen 4G: embryonic day 18.5 (more )
Note: Triple labeled: green - Ackr3; white - Cxcl12 (assay MGI:7616706); red - Cxcr4 (assay MGI:7616710).
Structure Level Pattern Image Note
TS26: lung vascular element Present Regionally restricted 4G Expression in capillary and venous endothelial cells.
Specimen 4H: embryonic day 18.5 (more )
Note: Triple labeled: green - Ackr3; white - Cxcl12 (assay MGI:7616706); red - Cxcr4 (assay MGI:7616710).
Structure Level Pattern Image Note
TS26: lung vascular element Present Regionally restricted 4H Expression in capillary and venous endothelial cells.
Specimen 4K: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: lung vascular element pulmonary capillary endothelial cell Present 4K
Specimen 4L: embryonic day 18.5 (more )
Note: Triple labeled: green - Ackr3; white - Cxcl12 (assay MGI:7616706); red - Cxcr4 (assay MGI:7616710).
Structure Cell Type Level Pattern Image Note
TS26: lung vascular element pulmonary capillary endothelial cell Present 4L
Specimen 4O: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lung vascular element Present Regionally restricted 4O Expression more prominent in venous enothelium.
Specimen S4H: embryonic day 18.5 (more )
Note: Double labeled: red - Ackr3; green - Nrg1 (assay MGI:7616711).
Structure Level Pattern Image Note
TS26: lung vascular element Present Regionally restricted S4H Expression almost exclusively in capillary and venous endothelium.
Specimen S4I: embryonic day 18.5 (more )
Note: Double labeled: red - Ackr3; white - Gpihbp1 (assay MGI:7616707).
Structure Level Pattern Image Note
TS26: lung vascular element Present Regionally restricted S4I Expression almost exclusively in capillary and venous endothelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory