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Gene Expression Data
Assay Details
Assay
Reference: J:65195 Stoykova A, et al., Pax6 modulates the dorsoventral patterning of the mammalian telencephalon. J Neurosci. 2000 Nov 1;20(21):8042-50
Assay type: RNA in situ
MGI Accession ID: MGI:7620210
Gene symbol: Nkx2-1
Gene name: NK2 homeobox 1
Probe: Nkx2.1 cDNA2
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 2C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Present Regionally restricted 2C Expression is in the germinative neuroepithelium and mantle.

Specimen 2C': embryonic day 13.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS21: lateral ganglionic eminence Present Regionally restricted 2C' In this mutant the expression domain had expanded beyond the border of the lateral and medial ganglionic eminences.
TS21: medial ganglionic eminence Present Regionally restricted 2C' In this mutant the expression domain had expanded beyond the border of the lateral and medial ganglionic eminences.

Specimen 2D: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: medial ganglionic eminence Present 2D

Specimen 2D': embryonic day 12.0; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS20: medial ganglionic eminence Present 2D'
TS20: lateral ganglionic eminence Present Regionally restricted 2D' Expression is in the ventricular zone.

Specimen 2E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: medial ganglionic eminence Present 2E

Specimen 2E': embryonic day 14.5; Pax6Sey/Pax6Sey (more )
Structure Level Pattern Image Note
TS22: medial ganglionic eminence Present 2E' The medial ganglionic eminence is enlarged in this mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory