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Gene Expression Data
Assay Details
Assay
Reference: J:146175 Bacon C, et al., Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system. J Comp Neurol. 2009 Mar 10;513(2):224-36
Assay type: RNA in situ
MGI Accession ID: MGI:7621450
Gene symbol: Srgap2
Gene name: SLIT-ROBO Rho GTPase activating protein 2
Probe: srGAP2 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: nasal pit Present 1B
TS19: trigeminal ganglion Present 1B
TS19: telencephalon Present Regionally restricted 1B Expression is in the preplate.
TS19: eye Present Regionally restricted 1B Expression is in the optic pit.
TS19: midbrain roof plate Present Regionally restricted 1B Expression is in the superior colliculus differentiating zone.
TS19: telencephalon ventricular layer Absent 1B
Specimen 1E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cortical plate Present 1E
TS21: cerebral cortex intermediate zone Weak 1E
Specimen 1H: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cortical plate Strong 1H
TS24: cerebral cortex intermediate zone Present 1H
TS24: cerebral cortex ventricular layer Present 1H
TS24: cortical subplate Absent 1H
Specimen 1K: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cortical layer II Strong 1K
TS28: cortical layer III Strong 1K
TS28: cortical layer IV Present 1K
TS28: cortical layer V Present 1K
TS28: cortical layer VI Present Diffuse 1K
TS28: cortical layer I Absent 1K
Specimen 2B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: thalamus Strong Non-Uniform 2B Expression is in the dorsal thalamus and is weaker in the ventral thalamus.
Specimen 2E: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: hippocampus CA3 Present 2E
TS27: hippocampus CA1 Weak 2E
TS27: dorsal thalamus Weak 2E
TS27: thalamus Weak 2E Expression was in the dorsal and ventral thalamus.
TS27: dentate gyrus Absent 2E
Specimen 2H: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: dorsal lateral geniculate nucleus Present 2H
TS28: hippocampus CA1 Present 2H
TS28: hippocampus CA3 Weak 2H
TS28: dentate gyrus Absent 2H
Specimen 3B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: midbrain roof plate Strong 3B Expression is stronger in the superior colliculus differentiating zone, and is largely absent from the superior colliculus neuroepithelium.
TS21: cerebellum Strong Regionally restricted 3B Expression is in the cerebellar plate and in the cerebellar nuclei differentiating zone.
Specimen 3B': embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebellum Present Regionally restricted 3B' Expression is in the cerebellar plate and in the cerebellar nuclei differentiating zone and is absent in the granule cells.
Specimen 3E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: inferior colliculus Strong Regionally restricted 3E Expression is in the superior and inferior colliculus differentiating zone.
TS24: superior colliculus Strong Regionally restricted 3E Expression is in the superior and inferior colliculus differentiating zone.
TS24: cerebellum Present Regionally restricted 3E Expression is in the cerebellar plate.
Specimen 3H: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cerebellum Purkinje cell layer Present 3H
TS27: tectum Weak Regionally restricted 3H Expression is in a region of the inferior colliculus.
Specimen 3K: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 3K
Specimen 4B: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: dorsal root ganglion Present 4B
TS19: neural tube floor plate Present 4B
TS19: neural tube roof plate Present 4B
TS19: neural tube commissural neuron Present Regionally restricted 4B Expression is in a population of commissural neurons positioned dorsolaterally.
Specimen 4E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 4E
TS20: spinal cord Present Ubiquitous 4E Expression is slightly elevated in the medial part of the cord
Specimen 4H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present Ubiquitous 4H
TS21: spinal cord Present Ubiquitous 4H
Specimen 5B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: olfactory epithelium Strong 5B
TS22: vomeronasal organ Strong 5B
TS22: main olfactory bulb mitral cell layer Present 5B
Specimen 5E: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: main olfactory bulb mitral cell layer Present 5E
TS27: olfactory epithelium Present 5E
Specimen 6B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: neural retina Weak Regionally restricted 6B Expression is in the retinal ganglion cell layer and is absent in the neuroblastic layer.
Specimen 6E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: retina ganglion cell layer Strong 6E
TS24: retina nuclear layer Absent 6E
Specimen Table 1 E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present
TS19: future spinal cord Present
TS19: nasal pit Present
TS19: neural tube floor plate Present
TS19: neural tube roof plate Present
TS19: neural retina Present Regionally restricted Expression is in the retinal ganglion layer, absent in the neuroblastic layer.
TS19: telencephalon Present Regionally restricted Expression is in the preplate.
TS19: midbrain roof plate Present Regionally restricted Expression is in the differentiating zone of the superior and inferior colliculi.
Specimen Table 1 E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cortical preplate Present
TS20: dorsal root ganglion Present
TS20: olfactory epithelium Present
TS20: spinal cord Present
TS20: spinal cord floor plate Present
TS20: spinal cord roof plate Present
TS20: vomeronasal organ Present
TS20: neural retina Present Regionally restricted Expression is in the retinal ganglion layer, absent in the neuroblastic layer.
TS20: brain nucleus Present Regionally restricted Expression is in the dorsal lateral geniculate nucleus and ventral lateral geniculate nucleus.
TS20: midbrain roof plate Present Regionally restricted Expression is in the differentiating zone of the superior and inferior colliculi.
TS20: cerebellum primordium Present Regionally restricted Expression is in the cerebellar nuclei differentiating zone and cerebellar plate.
TS20: cerebral cortex ventricular layer Absent
Specimen Table 1 E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex intermediate zone Present
TS21: cortical plate Present
TS21: dorsal root ganglion Present
TS21: olfactory epithelium Present
TS21: retina ganglion cell layer Present
TS21: spinal cord Present
TS21: spinal cord floor plate Present
TS21: spinal cord roof plate Present
TS21: vomeronasal organ Present
TS21: neural retinal epithelium Present Regionally restricted Expression is in the retinal ganglion layer, absent in the neuroblastic layer.
TS21: main olfactory bulb layer Present Regionally restricted Expression is in the mitral layer and is absent in the granule cell layer.
TS21: brain nucleus Present Regionally restricted Expression is in the dorsal lateral geniculate nucleus and ventral lateral geniculate nucleus.
TS21: midbrain roof plate Present Regionally restricted Expression is in the differentiating zone of the superior and inferior colliculi.
TS21: cerebellum Present Regionally restricted Expression is in the cerebellar nuclei differentiating zone and cerebellar plate.
TS21: cerebral cortex marginal layer Absent
TS21: cerebral cortex ventricular layer Absent
TS21: cortical subplate Absent
Specimen Table 1 E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cortical plate Present
TS22: dorsal lateral geniculate nucleus Present
TS22: hippocampus Present
TS22: main olfactory bulb mitral cell layer Present
TS22: olfactory epithelium Present
TS22: retina ganglion cell layer Present
TS22: ventral lateral geniculate nucleus Present
TS22: vomeronasal organ Present
TS22: neural retinal epithelium Present Regionally restricted Expression is in the retinal ganglion layer, absent in the neuroblastic layer.
TS22: main olfactory bulb layer Present Regionally restricted Expression is in the mitral layer and is absent in the granule cell layer.
TS22: inferior colliculus Present Regionally restricted Expression is in the differentiating zone of the superior and inferior colliculi.
TS22: superior colliculus Present Regionally restricted Expression is in the differentiating zone of the superior and inferior colliculi.
TS22: cerebellum Present Regionally restricted Expression is in the cerebellar plate.
TS22: cerebral cortex intermediate zone Absent
TS22: cerebral cortex marginal layer Absent
TS22: cerebral cortex ventricular layer Absent
TS22: cortical subplate Absent
Specimen Table 1 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex intermediate zone Present
TS24: cerebral cortex ventricular layer Present
TS24: cortical plate Present
TS24: dorsal lateral geniculate nucleus Present
TS24: hippocampus Present
TS24: main olfactory bulb mitral cell layer Present
TS24: olfactory epithelium Present
TS24: retina ganglion cell layer Present
TS24: superior colliculus Present
TS24: vomeronasal organ Present
TS24: inferior colliculus Present Regionally restricted Expression is in the differentiating zone.
TS24: cerebellum Present Regionally restricted Expression is in the cerebellar plate.
TS24: cerebral cortex marginal layer Absent
TS24: cortical subplate Absent
TS24: main olfactory bulb prospective granule cell layer Absent
TS24: retina nuclear layer Absent
TS24: ventral lateral geniculate nucleus Absent
Specimen Table 1 P1: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cerebellum Purkinje cell layer Present
TS27: cortical layer II Present
TS27: cortical layer III Present
TS27: cortical layer IV Present
TS27: cortical layer V Present
TS27: cortical layer VI Present
TS27: dorsal lateral geniculate nucleus Present
TS27: hippocampus CA1 Present
TS27: hippocampus CA3 Present
TS27: main olfactory bulb mitral cell layer Present
TS27: olfactory epithelium Present
TS27: ventral lateral geniculate nucleus Present
TS27: inferior colliculus Present Regionally restricted Expression is in the neuroepithelium.
TS27: cerebellum external granule cell layer Absent
TS27: cerebellum granule cell layer Absent
TS27: cerebellum molecular layer Absent
TS27: cerebral cortex ventricular zone Absent
TS27: cortical layer I Absent
TS27: dentate gyrus Absent
TS27: main olfactory bulb granule cell layer Absent
TS27: superior colliculus Absent
TS27: vomeronasal organ Absent
Specimen Table 1 P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present
TS28: cortical layer II Present
TS28: cortical layer III Present
TS28: cortical layer IV Present
TS28: cortical layer V Present
TS28: cortical layer VI Present
TS28: dorsal lateral geniculate nucleus Present
TS28: hippocampus CA1 Present
TS28: hippocampus CA3 Present
TS28: ventrolateral thalamic nucleus Present
TS28: cerebellum external granule cell layer Absent
TS28: cerebellum granule cell layer Absent
TS28: cerebellum molecular layer Absent
TS28: cerebral cortex ventricular zone Absent
TS28: cortical layer I Absent
TS28: deep cerebellar nucleus Absent
TS28: dentate gyrus Absent
TS28: ventral lateral geniculate nucleus Absent
TS28: ventral posterior lateral thalamic nucleus Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory