Gene Expression Data
Assay Details
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Assay
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Reference:
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J:291486
Daniel E, et al., Cyp26b1 is an essential regulator of distal airway epithelial differentiation during lung development. Development. 2020 Feb 20;147(4):dev181560
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7623752
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Gene symbol:
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Hopx
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Gene name:
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HOP homeobox
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Results
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Specimen
3A:
embryonic day 18.5
(more  )
Specimen
3A:
(close  )
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Genetic Background:
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involves: C57BL/6J * CD-1
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
3B:
(close )
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Genetic Background:
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involves: C57BL/6J * CD-1
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Mutant Allele(s):
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Cyp26b1em1Oncl/Cyp26b1em1Oncl
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: lung epithelium |
type I pneumocyte |
Present |
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3B
,
3B'
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A significant decrease in AT1 cells was observed in Cyp26b1-/- lungs.
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Specimen
4K:
embryonic day 16.5
(more )
Specimen
4K:
(close )
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Genetic Background:
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involves: C57BL/6J * CD-1
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: lung epithelium |
Present |
Regionally restricted |
4K
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Expression was detected in AT1 progenitors.
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Specimen
4L:
(close )
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Genetic Background:
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involves: C57BL/6J * CD-1
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Mutant Allele(s):
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Cyp26b1em1Oncl/Cyp26b1em1Oncl
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: lung epithelium |
Present |
Regionally restricted |
4L
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Immunostaining revealed no overt qualitative difference in AT1 progenitor patterning.
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Analysis Tools