Gene Expression Data
Assay Details
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Assay
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Reference:
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J:291486
Daniel E, et al., Cyp26b1 is an essential regulator of distal airway epithelial differentiation during lung development. Development. 2020 Feb 20;147(4):dev181560
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7623800
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Gene symbol:
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Sox9
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Gene name:
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SRY (sex determining region Y)-box 9
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Results
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Specimen
3G:
embryonic day 18.5
(more  )
Specimen
3G:
(close  )
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Genetic Background:
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involves: C57BL/6J * CD-1
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: lung epithelium |
Present |
Regionally restricted |
3G
,
3G'
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Expression was detected in distal lung epithelium.
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Specimen
3H:
(close )
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Genetic Background:
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involves: C57BL/6J * CD-1
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Mutant Allele(s):
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Cyp26b1em1Oncl/Cyp26b1em1Oncl
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: lung epithelium |
Present |
Regionally restricted |
3H
,
3H'
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There was an increase in Sox9+ distal epithelium cells in the Cyp26b1-/- lungs.
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Specimen
not shown +/+:
embryonic day 18.5
(more )
Specimen
not shown +/+:
(close )
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Genetic Background:
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involves: C57BL/6J * CD-1
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: lung epithelium |
Present |
Regionally restricted |
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Expression was detected in distal lung epithelium. Sox9+ cells could be Lamp3-immunopositive or Lamp3-negative.
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Specimen
not shown -/-:
(close )
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Genetic Background:
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involves: C57BL/6J * CD-1
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Mutant Allele(s):
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Cyp26b1em1Oncl/Cyp26b1em1Oncl
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: lung epithelium |
Present |
Regionally restricted |
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There was an increase in Sox9+/Lamp3+ distal epithelium cells in the Cyp26b1-/- lungs. The number of Sox9+/Lamp3- cells was not significantly changed.
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Specimen
S4E:
embryonic day 18.5
(more )
Specimen
S4E:
(close )
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Genetic Background:
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involves: C57BL/6J * CD-1
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: lung epithelium |
Present |
Regionally restricted |
S4E'
,
S4E
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Expression was detected in distal tip epithelial progenitors.
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Specimen
S4F:
(close )
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Genetic Background:
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involves: C57BL/6J * CD-1
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Mutant Allele(s):
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Cyp26b1em1Oncl/Cyp26b1em2Oncl
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: lung epithelium |
Present |
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S4F'
,
S4F
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There was an increase in Sox9+ distal tip epithelial progenitors in the Cyp26b1-/delta10 lungs.
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Analysis Tools