About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:346442 Migale R, et al., FOXL2 interaction with different binding partners regulates the dynamics of ovarian development. Sci Adv. 2024 Mar 22;10(12):eadl0788
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7628319
Gene symbol: Usp7
Gene name: ubiquitin specific peptidase 7
Antibody: anti-USP7 (A300-033A)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S15B Control: postnatal day 0; Usp7tm2Wgu/Usp7tm2Wgu (more )
Note: Double labeled: red - Usp7; green - Foxl2 (assay MGI:7628312).
Structure Level Pattern Image Note
TS27: ovary follicle cell Present Regionally restricted S15B Control FOXL2/USP7 , S15B Control USP7 Expression co-localized with Foxl2 in somatic cells.
TS27: oocyte Strong S15B Control FOXL2/USP7 , S15B Control USP7
Specimen S15B Sf1:Cretg/+;Usp7fl/fl: postnatal day 0; Tg(Nr5a1-cre)2Klp/0, Usp7tm2Wgu/Usp7tm2Wgu (more )
Note: Conditional mutant. Double labeled: red - Usp7; green - Foxl2 (assay MGI:7628312).
Structure Level Pattern Image Note
TS27: follicle cell of primordial follicle Absent S15B Sf1:Cretg/+;Usp7fl/fl FOXL2/USP7 , S15B Sf1:Cretg/+;Usp7fl/fl USP7 Expression not detected in somatic cells arrested in primordial follicle.
TS27: oocyte Strong S15B Sf1:Cretg/+;Usp7fl/fl FOXL2/USP7 , S15B Sf1:Cretg/+;Usp7fl/fl USP7
Specimen S15C Control: postnatal day 7; Usp7tm2Wgu/Usp7tm2Wgu (more )
Note: Double labeled: red - Usp7; green - Foxl2 (assay MGI:7628312).
Structure Level Pattern Image Note
TS28: ovary follicle cell Present S15C Control FOXL2/USP7 , S15C Control USP7 Expression co-localized with Foxl2 in somatic cells.
TS28: oocyte Strong S15C Control USP7 , S15C Control FOXL2/USP7
Specimen S15C Sf1:Cretg/+;Usp7fl/fl: postnatal day 7; Tg(Nr5a1-cre)2Klp/0, Usp7tm2Wgu/Usp7tm2Wgu (more )
Note: Conditional mutant. Double labeled: red - Usp7; green - Foxl2 (assay MGI:7628312).
Structure Level Pattern Image Note
TS28: follicle cell of primordial follicle Absent S15C Sf1:Cretg/+;Usp7fl/fl USP7 , S15C Sf1:Cretg/+;Usp7fl/fl FOXL2/USP7 Expression not detected in somatic cells arrested in primordial follicle.
TS28: oocyte Strong S15C Sf1:Cretg/+;Usp7fl/fl USP7 , S15C Sf1:Cretg/+;Usp7fl/fl FOXL2/USP7 Expression not detected in somatic cells arrested in primordial follicle.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory