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Gene Expression Data
Assay Details
Assay
Reference: J:166908 Sasaki T, et al., Regulation of hematopoietic cell clusters in the placental niche through SCF/Kit signaling in embryonic mouse. Development. 2010 Dec;137(23):3941-52
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7641778
Gene symbol: Itga2b
Gene name: integrin alpha 2b
Antibody: Anti-CD41
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3A: embryonic day 10.5 (more )
Note: Double labeled: green - Itga2b; red - Kit (assay MGI:7641742).
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone hematopoietic cell Absent 3A merge , 3A CD41
TS17: blood hematopoietic stem cell Present Single cells 3A merge , 3A CD41 Not coexpressed with Kit.
Specimen 3B: embryonic day 11.5 (more )
Note: Double labeled: green - Itga2b; red - Kit (assay MGI:7641742).
Structure Cell Type Level Pattern Image Note
TS19: labyrinthine zone hematopoietic cell Present Clusters 3B CD41 , 3B merge Coexpressed with Kit. The intensity of expression in hematopoietic cell clusters expressing Kit was relatively weak compared with single CD41/Itga2b+ cells.
TS19: blood hematopoietic stem cell Present Single cells 3B merge , 3B CD41 Not coexpressed with Kit.
Specimen 3C: embryonic day 11.5 (more )
Note: Double labeled: green - Itga2b; red - Kit (assay MGI:7641742).
Structure Cell Type Level Pattern Image Note
TS19: labyrinthine zone hematopoietic cell Present Clusters 3C CD41 , 3C merge Coexpressed with Kit.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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