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Gene Expression Data
Assay Details
Assay
Reference: J:312371 Da Silva F, et al., Mitotic WNT signalling orchestrates neurogenesis in the developing neocortex. EMBO J. 2021 Oct 1;40(19):e108041
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7643178
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6 (#PRB-278P; #30130, #901301)
Detection system: Secondary antibody
Results
Specimen 2A Co: embryonic day 13.5; Ccnytm1.1Smoc/Ccny+, Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1+ (more )
Note: Double labeled: red - Pax6; green - BrdU.
Structure Cell Type Level Pattern Image Note
TS21: cerebral cortex ventricular layer neural progenitor cell Present 2A Co Expressed in the apical progenitors.
Specimen 2A DKO: embryonic day 13.5; Ccnytm1.1Smoc/Ccnytm1.1Smoc, Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1tm1a(EUCOMM)Wtsi (more )
Note: Double labeled: red - Pax6; green - BrdU.
Structure Cell Type Level Pattern Image Note
TS21: cerebral cortex ventricular layer neural progenitor cell Present 2A DKO Positive apical progenitors in S phase were slightly increased compared with the control (quantified in Fig 2B).
Specimen not shown Co: embryonic day 11.5; Ccnytm1.1Smoc/Ccny+, Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1+ (more )
Structure Cell Type Level Pattern Image Note
TS19: telencephalon ventricular layer neural progenitor cell Present Expressed in the apical progenitors.
Specimen not shown DKO: embryonic day 11.5; Ccnytm1.1Smoc/Ccnytm1.1Smoc, Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1tm1a(EUCOMM)Wtsi (more )
Structure Cell Type Level Pattern Image Note
TS19: telencephalon ventricular layer neural progenitor cell Present Positive apical progenitors in S phase were similar as in the control (quantified in Fig 2B).
Specimen not shown Co: embryonic day 12.5; Ccnytm1.1Smoc/Ccny+, Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1+ (more )
Structure Cell Type Level Pattern Image Note
TS20: cerebral cortex ventricular layer neural progenitor cell Present Expressed in the apical progenitors.
Specimen not shown DKO: embryonic day 12.5; Ccnytm1.1Smoc/Ccnytm1.1Smoc, Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1tm1a(EUCOMM)Wtsi (more )
Structure Cell Type Level Pattern Image Note
TS20: cerebral cortex ventricular layer neural progenitor cell Present Positive apical progenitors in S phase were similar as in the control (quantified in Fig 2B).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory