Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:312371 Da Silva F, et al., Mitotic WNT signalling orchestrates neurogenesis in the developing neocortex. EMBO J. 2021 Oct 1;40(19):e108041
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7643181
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:	anti-activated Caspase 3 (AF835)
Detection system:	Secondary antibody coupled to Alexa Fluor 488
Assay notes:	The antibody used recognizes the cleaved form of the protein.

Results

2N Co ©

Specimen 2N Co: embryonic day 13.5; Ccny^tm1.1Smoc/Ccny⁺, Ccnyl1^{tm1a(EUCOMM)Wtsi}/Ccnyl1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS21: neocortex	Present		2N Co

2N DKO ©

Specimen 2N DKO: embryonic day 13.5; Ccny^tm1.1Smoc/Ccny^tm1.1Smoc, Ccnyl1^{tm1a(EUCOMM)Wtsi}/Ccnyl1^{tm1a(EUCOMM)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS21: neocortex	Present		2N DKO	Similar as in the control.

Specimen not shown Co: embryonic day 11.5; Ccny^tm1.1Smoc/Ccny⁺, Ccnyl1^{tm1a(EUCOMM)Wtsi}/Ccnyl1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS19: telencephalon	Present

Specimen not shown DKO: embryonic day 11.5; Ccny^tm1.1Smoc/Ccny^tm1.1Smoc, Ccnyl1^{tm1a(EUCOMM)Wtsi}/Ccnyl1^{tm1a(EUCOMM)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS19: telencephalon	Present			A minor, however statistically not significant, increase in the neocortex compared with the control.

Specimen not shown Co: embryonic day 12.5; Ccny^tm1.1Smoc/Ccny⁺, Ccnyl1^{tm1a(EUCOMM)Wtsi}/Ccnyl1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS20: neocortex	Present

Specimen not shown DKO: embryonic day 12.5; Ccny^tm1.1Smoc/Ccny^tm1.1Smoc, Ccnyl1^{tm1a(EUCOMM)Wtsi}/Ccnyl1^{tm1a(EUCOMM)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS20: neocortex	Present			Similar as in the control.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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