About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:195264 Vincentz JW, et al., Twist1 Controls a Cell-Specification Switch Governing Cell Fate Decisions within the Cardiac Neural Crest. PLoS Genet. 2013 Mar;9(3):e1003405
Assay type: RNA in situ
MGI Accession ID: MGI:7643412
Gene symbol: Hey2
Gene name: hairy/enhancer-of-split related with YRPW motif 2
Probe: Hey2 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen S2E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: outflow tract endocardial cushion Present Regionally restricted S2E Expression was detected in aorticopulmonary cushion mesenchyme.
Specimen S2F: embryonic day 11.5; H2az2Tg(Wnt1-cre)11Rth/0, Twist1tm1Bhr/Twist1tm2Bhr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: outflow tract endocardial cushion Present Regionally restricted S2F Conditional ablation of Twist1 produces abnormal cellular aggregates. Expression of Hey2 was absent from the aggregates, but was expressed in surrounding ecto-mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory