About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:195264 Vincentz JW, et al., Twist1 Controls a Cell-Specification Switch Governing Cell Fate Decisions within the Cardiac Neural Crest. PLoS Genet. 2013 Mar;9(3):e1003405
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7643415
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: Anti-Tubb3
Detection system: Secondary antibody coupled to DyLight
Results
Specimen 1G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: outflow tract endocardial cushion Absent 1G Expression was not detected in the aorticopulmonary cushion tissue of the control.
Specimen 1H: embryonic day 11.5; H2az2Tg(Wnt1-cre)11Rth/0, Twist1tm1Bhr/Twist1tm2Bhr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: outflow tract endocardial cushion Present Regionally restricted 1H Conditional ablation of Twist1 produces abnormal cellular aggregates. Expression of Tubb3 was detected in the aggregates.
Specimen not shown: embryonic day 11.5; Twist1tm1Bhr/Twist1tm2Bhr, Hand1tm1.1(EGFP/cre)Abfi/Hand1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: outflow tract endocardial cushion Present Regionally restricted Conditional ablation of Twist1 produces abnormal cellular aggregates. Expression of Tubb3 was detected in the aggregates.
Specimen 8D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: thoracic ganglion Present 8D Expression was detected in the thoracic sympathetic chain ganglia.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory