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Gene Expression Data
Assay Details
Assay
Reference: J:195264 Vincentz JW, et al., Twist1 Controls a Cell-Specification Switch Governing Cell Fate Decisions within the Cardiac Neural Crest. PLoS Genet. 2013 Mar;9(3):e1003405
Assay type: RNA in situ
MGI Accession ID: MGI:7643450
Gene symbol: Chat
Gene name: choline O-acetyltransferase
Probe: IMAGE clone 8734071
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen S4M: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: outflow tract endocardial cushion Absent S4M

Specimen S4N: embryonic day 11.5; H2az2Tg(Wnt1-cre)11Rth/0, Twist1tm1Bhr/Twist1tm2Bhr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: outflow tract endocardial cushion Absent S4N Conditional ablation of Twist1 produces abnormal cellular aggregates. Expression of Chat was not above background levels in the aggregates.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory