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Gene Expression Data
Assay Details
Assay
Reference: J:344830 Tsutsumi-Arai C, et al., A PTHrP Gradient Drives Mandibular Condylar Chondrogenesis via Runx2. J Dent Res. 2024 Jan;103(1):91-100
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7645423
Gene symbol: Pthlh
Gene name: parathyroid hormone-like peptide
Antibody: anti-PTHrP (PA5-57493)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen 2B Control: embryonic day 18.5; Pthlhem1Nono/Pthlh+ (more )
Note: Double labeled: yellow - Pthlh protein; red - Pthlh reporter (assay MGI:7645376).
Structure Level Pattern Image Note
TS26: mandible condylar process Present Regionally restricted 2B Control PTHrP Expression is in the superficial layer of the mandibular condylar cartilage.
Specimen 2B KO: embryonic day 18.5; Pthlhem1Nono/Pthlhem1Nono (more )
Note: Double labeled: yellow - Pthlh protein; red - Pthlh reporter (assay MGI:7645376).
Structure Level Pattern Image Note
TS26: mandible condylar process Absent 2B KO PTHrP
Specimen 2C Polymorphic: embryonic day 18.5; Pthlhem1Nono/Pthlh+ (more )
Note: Double labeled: yellow - Pthlh protein; red - Pthlh reporter (assay MGI:7645376).
Structure Level Pattern Image Note
TS26: mandible condylar process Present Regionally restricted 2C Polymorphic Expression is in the superficial layer of the mandibular condylar cartilage.
Specimen 2C Chondrocyte: embryonic day 18.5; Pthlhem1Nono/Pthlh+ (more )
Note: Double labeled: yellow - Pthlh protein; red - Pthlh reporter (assay MGI:7645376).
Structure Level Pattern Image Note
TS26: mandible condylar process Present Regionally restricted 2C Chondrocyte Expression is in the superficial layer of the mandibular condylar cartilage.
Specimen S1D: postnatal day 3; Pthlhem1Nono/Pthlh+ (more )
Note: Double labeled: yellow - Pthlh protein; red - Pthlh reporter (assay MGI:7645376).
Structure Level Pattern Image Note
TS27: mandible condylar process Present Regionally restricted S1D PTHrP
Specimen S1E Polymorphic: postnatal day 3; Pthlhem1Nono/Pthlh+ (more )
Note: Double labeled: yellow - Pthlh protein; red - Pthlh reporter (assay MGI:7645376).
Structure Level Pattern Image Note
TS27: mandible condylar process Present Regionally restricted S1E Polymorphic layer Expression is in the polymorphic and flattened chondrocyte layers but not in the hypertrophic chondrocyte layer.
Specimen S1E Chondrocyte: postnatal day 3; Pthlhem1Nono/Pthlh+ (more )
Note: Double labeled: yellow - Pthlh protein; red - Pthlh reporter (assay MGI:7645376).
Structure Level Pattern Image Note
TS27: mandible condylar process Present Regionally restricted S1E Chondrocyte layer Expression is in the polymorphic and flattened chondrocyte layers but not in the hypertrophic chondrocyte layer.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/22/2024
MGI 6.24 		The Jackson Laboratory