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Gene Expression Data
Assay Details
Assay
Reference: J:305426 Du G, et al., Proper timing of a quiescence period in precursor prospermatogonia is required for stem cell pool establishment in the male germline. Development. 2021 May 1;148(9):dev194571
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7662974
Gene symbol: Stra8
Gene name: stimulated by retinoic acid gene 8
Antibody: anti-STRA8
Detection system: Secondary antibody
Results
Specimen 5G Control: embryonic day 16.5 (more )
Note: Double labeled: green - Stra8; red - Gcna (assay MGI:7662958).
Structure Level Pattern Image Note
TS24: germ cell of testis Present 5G Control STRA8 , 5G Control Merge Expression is in prospermatogonia.
Specimen 5G Rb1-cKOBlimp1: embryonic day 16.5; Rb1tm2Brn/Rb1tm2Brn, Tg(Prdm1-cre)1Masu/0 (more )
Note: Conditional mutant. Double labeled: green - Stra8; red - Gcna (assay MGI:7662958).
Structure Level Pattern Image Note
TS24: germ cell of testis Present 5G Rb1-cKOBlimp1 Merge , 5G Rb1-cKOBlimp1 STRA8 In this mutant there was an about 18-fold increase in the percentage of positive cells compared to controls.
Specimen S7B Control: embryonic day 18.5 (more )
Note: Double labeled: green - Stra8; red - Gcna (assay MGI:7662958).
Structure Level Pattern Image Note
TS26: germ cell of testis Present S7B Control Merge , S7B Control STRA8 Expression is in prospermatogonia.
Specimen S7B Rb1-cKOBlimp1: embryonic day 18.5; Rb1tm2Brn/Rb1tm2Brn, Tg(Prdm1-cre)1Masu/0 (more )
Note: Conditional mutant. Double labeled: green - Stra8; red - Gcna (assay MGI:7662958).
Structure Level Pattern Image Note
TS26: germ cell of testis Present S7B Rb1-cKOBlimp1 STRA8 , S7B Rb1-cKOBlimp1 Merge There was an about 50% increase in expression in this mutant compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory