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Gene Expression Data
Assay Details
Assay
Reference: J:201463 Watson LA, et al., Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span. J Clin Invest. 2013 May 1;123(5):2049-63
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7705373
Gene symbol: Atrx
Gene name: ATRX, chromatin remodeler
Antibody: anti-ATRX
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 7C Ctrl: postnatal day 23; Foxg1tm1(cre)Skm/Foxg1+ (more )
Structure Level Pattern Image Note
TS28: adenohypophysis Present 7C Ctrl left , 7C Ctrl right
TS28: adenohypophysis pars intermedia Present 7C Ctrl left , 7C Ctrl right
TS28: neurohypophysis pars nervosa Present 7C Ctrl left , 7C Ctrl right
Specimen 7C cKO: postnatal day 23; Atrxtm1Rjg/Y, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: adenohypophysis Absent 7C cKO right , 7C cKO left
TS28: adenohypophysis pars intermedia Absent 7C cKO right , 7C cKO left
Specimen 7D Ctrl: embryonic day 13.5; Foxg1tm1(cre)Skm/Foxg1+ (more )
Structure Level Pattern Image Note
TS21: adenohypophysis Present 7D Ctrl
Specimen 7D cKO: embryonic day 13.5; Atrxtm1Rjg/Y, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: adenohypophysis Absent 7D cKO
Specimen S1B Ctrl: postnatal day 7; Foxg1tm1(cre)Skm/Foxg1+ (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present S1B Ctrl
Specimen S1B cKO: postnatal day 7; Atrxtm1Rjg/Y, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebral cortex Absent S1B cKO
Specimen S4D Ctrl: postnatal day 20; Foxg1tm1(cre)Skm/Foxg1+ (more )
Structure Level Pattern Image Note
TS28: tibia Present Regionally restricted S4D Ctrl Expressed in the growth plate.
Specimen S4D cKO: postnatal day 20; Atrxtm1Rjg/Y, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: tibia Present S4D cKO Expressed in the growth plate, similar as in the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/09/2024
MGI 6.24 		The Jackson Laboratory