Gene Expression Data
Assay Details
Assay
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Reference:
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J:54931
Finotto S, et al., Analysis of mice carrying targeted mutations of the glucocorticoid receptor gene argues against an essential role of glucocorticoid signalling for generating adrenal chromaffin cells. Development. 1999 Jul;126(13):2935-44
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7709678
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Gene symbol:
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Chgb
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Gene name:
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chromogranin B
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Antibody:
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anti-chromogranin B
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to Cy3
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Results
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Specimen
E18.5 wt not shown:
embryonic day 18.5
(more )
Note: Additional data presented in Table 2.
Specimen
E18.5 wt not shown:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Additional data presented in Table 2.
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Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS26: adrenal gland |
chromaffin cell of adrenal gland |
Moderate |
Regionally restricted |
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Expression in most of chromaffin cells.
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Specimen
E18.5 hypo/hypo not shown:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Nr3c1tm1Gsc/Nr3c1tm1Gsc
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Structure |
Level |
Pattern |
Image |
Note |
TS26: adrenal gland |
Weak |
Regionally restricted |
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Numbers of expressing cells diminished compared to wild type.
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Specimen
E18.5 null/null not shown:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Nr3c1tm2.1Gsc/Nr3c1tm2.1Gsc
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: adrenal gland |
Weak |
Regionally restricted |
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Numbers of expressing cells diminished compared to wild type.
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