Tfam Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:321836 Zhao K, et al., LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development. Development. 2022 Mar 15;149(6):dev200458
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7712139
Gene symbol:	Tfam
Gene name:	transcription factor A, mitochondrial

Antibody:	TFAM Polyclonal antibody (22586-1-AP)
Detection system:	Secondary antibody

Results

6C Ctrl TFAM ©

6C' ©

Specimen 6C Ctrl: embryonic day 12.5 (more

)
Note: Double labeled: green - Tfam; red - alpha-actinin.

Structure	Level	Pattern	Image	Note
TS20: heart	Present		6C Ctrl merge , 6C Ctrl TFAM , 6C'

6C cKO merge ©

6C cKO TFAM ©

6C" ©

Specimen 6C cKO: embryonic day 12.5; Lonp1^tm1.1Zzy/Lonp1^tm1.1Zzy, Tg(Tnnt2-cre)5Blh/0 (more

)
Note: Conditional mutant. Double labeled: green - Tfam; red - alpha-actinin.

Structure	Level	Pattern	Image	Note
TS20: heart	Present		6C cKO merge , 6C cKO TFAM , 6C"	A profound decrease was seen, compared with the control.

Specimen S6B Ctrl: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: heart	Present		S6B Ctrl TFAM

S6B cKO TFAM ©

Specimen S6B cKO: embryonic day 10.5; Lonp1^tm1.1Zzy/Lonp1^tm1.1Zzy, Tg(Tnnt2-cre)5Blh/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS17: heart	Present		S6B cKO TFAM	Similar as in the control.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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