About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:332292 Zhang Y, et al., Mutations in the TBX15-ADAMTS2 pathway associate with a novel soft palate dysplasia. Hum Mutat. 2022 Dec;43(12):2102-2115
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7717002
Gene symbol: Adamts2
Gene name: ADAM metallopeptidase with thrombospondin type 1 motif 2
Antibody: anti-ADAMTS2 (ab125226)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 5b1,b2,b3: embryonic day 13.5 (more )
Note: Double labeled: green - Adamts2; brown - Tbx15 (assay MGI:7717001).
Structure Level Pattern Image Note
TS21: secondary palate Present Regionally restricted 5b1 , 5d1 , 5b2 , 5b3 , 5d2 , 5d3 Expression in posterior palate co-localized with Tbx15 expression in posterior palatal mesenchymal cells.
Specimen 5b4,b5: embryonic day 15.5 (more )
Note: Double labeled: green - Adamts2; brown - Tbx15 (assay MGI:7717001).
Structure Level Pattern Image Note
TS23: secondary palate Present Regionally restricted 5d4 , 5b5 , 5b4 , 5d5 Expression in posterior palate co-localized with Adamts2 expression in fused palatal shelves at E15.5.
Specimen 5b6,b7: embryonic day 18.5 (more )
Note: Double labeled: green - Adamts2; brown - Tbx15 (assay MGI:7717001).
Structure Level Pattern Image Note
TS26: secondary palate Present 5b7 , 5d6 , 5d7 , 5b6 Expression in posterior palate.
Specimen 6a1,a2,a3: embryonic day 13.5 (more )
Note: Triple labeled: green - Adamts2; red - Col1a1 (assay MGI:7717004); brown - Sox9 (assay MGI:7717003).
Structure Level Pattern Image Note
TS21: secondary palate Present Regionally restricted 6a2 , 6e2 , 6e3 , 6e1 , 6a1 , 6a3 Expression in middle palate.
Specimen 6a4,a5,a6: embryonic day 13.5 (more )
Note: Triple labeled: green - Adamts2; red - Col1a1 (assay MGI:7717004); brown - Sox9 (assay MGI:7717003).
Structure Level Pattern Image Note
TS21: secondary palate Present 6e6 , 6e5 , 6a6 , 6e4 , 6a4 , 6a5 Expression in posterior palate.
Specimen S2a1,a2: embryonic day 15.5 (more )
Note: Triple labeled: green - Adamts2; red - Col1a1 (assay MGI:7717004); brown - Sox9 (assay MGI:7717003).
Structure Level Pattern Image Note
TS21: secondary palate Present Regionally restricted S2e2 , S2a2 , S2a1 , S2e1 Expression in middle palate.
Specimen S2a3,a4: embryonic day 15.5 (more )
Note: Triple labeled: green - Adamts2; red - Col1a1 (assay MGI:7717004); brown - Sox9 (assay MGI:7717003).
Structure Level Pattern Image Note
TS23: secondary palate Present S2a4 , S2a3 , S2e3 , S2e4 Expression in posterior palate.
Specimen S2a5,a6: embryonic day 18.5 (more )
Note: Triple labeled: green - Adamts2; red - Col1a1 (assay MGI:7717004); brown - Sox9 (assay MGI:7717003).
Structure Level Pattern Image Note
TS26: secondary palate Present S2a6 , S2e6 , S2e5 , S2a5 Expression in middle palate.
Specimen S2a7,a8: embryonic day 18.5 (more )
Note: Triple labeled: green - Adamts2; red - Col1a1 (assay MGI:7717004); brown - Sox9 (assay MGI:7717003).
Structure Level Pattern Image Note
TS26: secondary palate Present S2e7 , S2a7 , S2e8 , S2a8 Expression in posterior palate.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/17/2024
MGI 6.24 		The Jackson Laboratory