Gene Expression Data
Assay Details
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Assay
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Reference:
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J:171072
Carre A, et al., Hes1 is required for appropriate morphogenesis and differentiation during mouse thyroid gland development. PLoS One. 2011;6(2):e16752
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7720376
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Gene symbol:
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Ascl1
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Gene name:
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achaete-scute family bHLH transcription factor 1
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Antibody:
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anti-Mash1
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Detection system:
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Secondary antibody coupled to horseradish peroxidase
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Results
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Specimen
1P:
embryonic day 13.5
(more  )
Specimen
1P:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Specimen
3E:
embryonic day 16.5
(more )
Specimen
3E:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS24: thyroid gland |
parafollicular cell |
Present |
Scattered |
3E
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Expressed in in C-cells scattered throughout the gland in a parafollicular position.
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Specimen
3J:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Mutant Allele(s):
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Hes1tm1Fgu/Hes1tm1Fgu
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: thyroid gland |
Present |
Clusters |
3J
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Positive cells were clustered in a specific region.
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Specimen
3O:
embryonic day 15.5
(more )
Specimen
3O:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS23: thyroid gland |
parafollicular cell |
Present |
Scattered |
3O
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Specimen
3T:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Mutant Allele(s):
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Hes1tm1Fgu/Hes1tm1Fgu
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: thyroid gland |
Present |
Single cells |
3T
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Few positive cells were seen in the mutant, localized at the cranial part.
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Analysis Tools