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Gene Expression Data
Assay Details
Assay
Reference: J:171072 Carre A, et al., Hes1 is required for appropriate morphogenesis and differentiation during mouse thyroid gland development. PLoS One. 2011;6(2):e16752
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7720403
Gene symbol: Pax8
Gene name: paired box 8
Antibody: anti-Pax8
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3C: embryonic day 16.5 (more )
Note: Double labeled: green - Pax8; red - Tg (assay MGI:7720377).
Structure Cell Type Level Pattern Image Note
TS24: thyroid gland thyroid follicular cell Present 3C Expressed in TG-producing thyrocytes organized in small thyroid follicles.

Specimen 3H: embryonic day 16.5; Hes1tm1Fgu/Hes1tm1Fgu (more )
Note: Double labeled: green - Pax8; red - Tg (assay MGI:7720377).
Structure Level Pattern Image Note
TS24: thyroid gland Present Scattered 3H Positive cells scattered throughout the gland.

Specimen 3M: embryonic day 15.5 (more )
Note: Double labeled: green - Pax8; red - Tg (assay MGI:7720377).
Structure Cell Type Level Pattern Image Note
TS23: thyroid gland lobe thyroid follicular cell Present 3M Expressed in TG-producing thyrocytes organized in small thyroid follicles.

Specimen 3R: embryonic day 15.5; Hes1tm1Fgu/Hes1tm1Fgu (more )
Note: Double labeled: green - Pax8; red - Tg (assay MGI:7720377).
Structure Level Pattern Image Note
TS23: thyroid gland Present Regionally restricted 3R Expressed a moderate number of positive cells in the ultimobranchial bodies in the mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory