exudative vitreoretinopathy Disease Ontology Browser

Disease Ontology Browser

exudative vitreoretinopathy (DOID:0050535)
Alliance: disease page
Synonyms: familial exudative vitreoretinopathy; FEVR
Alt IDs: ICD10CM:H35.00, ICD9CM:362.10, OMIM:PS133780, ORDO:891, UMLS_CUI:C0004608
Definition: A retinal vascular disease characterized by the prevention of blood vessel formation at the edges of the retina and the hemorrhage of the blood vessels in the retina.

Term Browser
Genes (12)
Models (12)

Disease References using Mouse Models (4)

Mouse Models

Human Disease Modeled: exudative vitreoretinopathy
Associated Mouse Gene: Cdh5

Allelic Composition	Genetic Background	Reference	Phenotypes
Cdh5tm1Dvst/Cdh5tm1Dvst Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0	involves: C57BL/6 * CBA	J:328283	View

Mouse Models

Human Disease Modeled: exudative vitreoretinopathy
Associated Mouse Gene: Ctnnb1

Allelic Composition	Genetic Background	Reference	Phenotypes
Ctnnb1em1V/Ctnnb1em1V Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0	involves: C57BL/6 * C57BL/6J * CBA	J:328283	View

Mouse Models

Human Disease Modeled: exudative vitreoretinopathy
Associated Mouse Gene: Fzd4

Allelic Composition	Genetic Background	Reference	Phenotypes
Fzd4tm1Nat/Fzd4tm1Nat	involves: 129S1/Sv * 129X1/SvJ	J:158585	View
Fzd4tm1Nat/Fzd4tm1Nat	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	J:328283	View

Mouse Models

Human Disease Modeled: exudative vitreoretinopathy
Associated Mouse Gene: Lrp5

Allelic Composition	Genetic Background	Reference	Phenotypes
Lrp5r18/Lrp5r18	C57BL/6J-Lrp5^r18	J:135279	View
Lrp5tm1Dgen/Lrp5tm1Dgen	B6.129P2-Lrp5^tm1Dgen/J	J:235600	View
Lrp5em1Xjz/Lrp5em1Xjz	C57BL/6J-Lrp5^em1Xjz	J:328283	View
Lrp5tm1Dgen/Lrp5tm1Dgen	involves: 129P2/OlaHsd * C57BL/6	J:328283	View

Mouse Models

Human Disease Modeled: exudative vitreoretinopathy
Associated Mouse Gene: Ndp

Allelic Composition	Genetic Background	Reference	Phenotypes
Ndptm1Wbrg/Y	involves: 129P2/OlaHsd * C57BL/6	J:158585	View

Mouse Models

Human Disease Modeled: exudative vitreoretinopathy
Associated Mouse Gene: Tspan12

Allelic Composition	Genetic Background	Reference	Phenotypes
Tspan12tm1Wye/Tspan12tm1Wye	either: B6.129S5-Tspan12^tm1Wye or FVB.129S5-Tspan12^tm1Wye	J:158585	View

Mouse Models

Human Disease Modeled: exudative vitreoretinopathy

Allelic Composition	Genetic Background	Reference	Phenotypes
Ctnna1tm1Efu/Ctnna1tm1Efu Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0	involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * C57BL/6NCrl * CBA	J:328283	View

Mouse Models

Human Disease Modeled: exudative vitreoretinopathy

Allelic Composition	Genetic Background	Reference	Phenotypes
Ctnna1em1Xjz/Ctnna1tm1Efu Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0	involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * C57BL/6J * C57BL/6NCrl * CBA	J:328283	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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