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Disease Ontology Browser
aromatase excess syndrome (DOID:0090122)
Alliance: disease page
Synonyms: AEXS; familial hyperestrogenism; hereditary prepubertal gynecomastia; increased aromatase activity
Alt IDs: OMIM:139300, ICD10CM:E30.1, ORDO:178345
Definition: A reproductive system disease characterized by increased extraglandular aromatization of steroids resulting in heterosexual precocity in males and isosexual precocity in females, and has_material_basis_in autosomal dominant inheritance of fusion of the aromatase gene (CYP19A1) with various partners, brought about by translocations and resulting in gain of function of the CYP19A1 gene.

Disease References using Mouse Models (1)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory