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Disease Ontology Browser
angle-closure glaucoma (DOID:13550)
Alliance: disease page
Synonyms: ACG - Angle-closure glaucoma; Angle Closure Glaucoma; Closed angle glaucoma; Narrow cleft glaucoma; primary open-angle glaucoma with narrow angles
Alt IDs: MESH:D015812, NCI:C34639, UMLS_CUI:C0017605
Definition: A glaucoma characterized by closure of the anterior chamber angle such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Angle-closure glaucoma has_symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Angle closure glaucoma can be caused by anatomically narrow angle, injury to the trabecular meshwork, and injuries to the anterior chamber, such as neovascularization and uveitis.

Disease References using Mouse Models (2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory