exfoliation syndrome Disease Ontology Browser

Disease Ontology Browser

exfoliation syndrome (DOID:13641)
Alliance: disease page
Synonyms: Pseudoexfoliation glaucoma; Pseudoexfoliation syndrome
Alt IDs: OMIM:177650, EFO:0004235, ICD9CM_2006:365.52, ICD9CM:365.52, MESH:D017889, NCI:C129025, UMLS_CUI:C0206368
Definition: A phacogenic glaucoma that is characterized by open-angle glaucoma related to deposition of extracellular fibrillar material in anterior segment structures, which blocks aqueous fluid outflow, raises intraocular pressure, and leads to eventual optic nerve atrophy and visual field loss. Exfoliation syndrome has_symptom progressive decreased vision, especially peripheral vision. Exfoliation syndrome is caused by age-related deposition of fibrillar material in anterior segment structures.

Disease References using Mouse Models (3)

Allelic Composition	Genetic Background	Reference	Phenotypes
Loxl1tm1Tili/Loxl1tm1Tili	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	J:229298	View

Allelic Composition	Genetic Background	Reference	Phenotypes
Lystbg-J/Lystbg-J	C57BL/6J-Lyst^bg-J/J	J:173521	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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