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Disease Ontology Browser
autoimmune lymphoproliferative syndrome (DOID:6688)
Alliance: disease page
Synonyms: ALPS; Canale-Smith syndrome
Alt IDs: OMIM:601859, ICD10CM:D89.82, ICD9CM:279.41, MESH:D056735, NCI:C37864, ORDO:3261, UMLS_CUI:C1328840
Definition: A hypersensitivity reaction type IV disease that is an inherited disorder in which the body cannot properly regulate the number of immune system cells (lymphocytes). It is characterized by the production of an abnormally large number of lymphocytes. Accumulation of excess lymphocytes results in enlargement of the lymph nodes, the liver, and the spleen.

Disease References using Mouse Models (7)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory