osteoarthritis Disease Ontology Browser

Disease Ontology Browser

osteoarthritis (DOID:8398)
Alliance: disease page
Synonyms: degenerative arthritis; degenerative joint disease; hypertrophic arthritis; osteoarthrosis; Osteoarthrosis and allied disorder
Alt IDs: ICD9CM:715.3, UMLS_CUI:C0157946
Definition: An arthritis that has_material_basis_in worn out cartilage located_in joint.

Term Browser
Genes (42)
Models (15)

Disease References using Mouse Models (24)

Mouse Models

Human Disease Modeled: osteoarthritis
Associated Mouse Gene: Gdf5

Allelic Composition	Genetic Background	Reference	Phenotypes
Gdf5Rgsc451/Gdf5Rgsc451	C57BL/6JJcl-Gdf5^Rgsc451	J:125122	View

Mouse Models

Human Disease Modeled: osteoarthritis
Associated Mouse Gene: Matn3

Allelic Composition	Genetic Background	Reference	Phenotypes
Matn3tm1Brd/Matn3tm1Brd	involves: 129S7/SvEvBrd * C57BL/6	J:112002	View

Mouse Models

Human Disease Modeled: osteoarthritis
Associated Mouse Gene: Atp7a

Allelic Composition	Genetic Background	Reference	Phenotypes
Atp7aMo-blo/Y	B6.Cg-Atp7a^Mo-blo/J	J:36378	View

Mouse Models

Human Disease Modeled: osteoarthritis
Associated Mouse Gene: Bmp7

Allelic Composition	Genetic Background	Reference	Phenotypes
Bmp7tm1.1Dgra/Bmp7tm1.1Dgra Tg(Prrx1-cre)1Cjt/0	involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac * SJL/J	J:221175	View

Mouse Models

Human Disease Modeled: osteoarthritis
Associated Mouse Gene: Bmpr1a

Allelic Composition	Genetic Background	Reference	Phenotypes
Bmpr1atm2.1Bhr/Bmpr1atm2.2Bhr Tg(Gdf5-cre,-ALPP)1Kng/0	involves: 129 * C57BL/6 * FVB/N-Tg(Gdf5-cre-ALPP)1Kng	J:97780	View

Mouse Models

Human Disease Modeled: osteoarthritis
Associated Mouse Gene: Col9a1

Allelic Composition	Genetic Background	Reference	Phenotypes
Col9a1tm1Jae/Col9a1tm1Jae	involves: 129S2/SvPas	J:117910	View

Mouse Models

Human Disease Modeled: osteoarthritis
Associated Mouse Gene: Col11a1

Allelic Composition	Genetic Background	Reference	Phenotypes
Col11a1cho/Col11a1+	involves: C57BL/6Fr	J:106282	View

Mouse Models

Human Disease Modeled: osteoarthritis
Associated Mouse Gene: Enpp1

Allelic Composition	Genetic Background	Reference	Phenotypes
Enpp1ttw/Enpp1ttw	involves: ICR	J:37369, J:19124	View

Mouse Models

Human Disease Modeled: osteoarthritis
Associated Mouse Gene: Erg

Allelic Composition	Genetic Background	Reference	Phenotypes
Ergtm1.1Iwamo/Ergtm1.1Iwamo Tg(Gdf5-cre,-ALPP)1Kng/?	involves: 129S4/SvJaeSor * C57BL/6 * FVB/N	J:243715	View

Mouse Models

Human Disease Modeled: osteoarthritis
Associated Mouse Gene: Errfi1

Allelic Composition	Genetic Background	Reference	Phenotypes
Errfi1tm1Gvw/Errfi1tm1Gvw	Not Specified	J:100927	View

Mouse Models

Human Disease Modeled: osteoarthritis
Associated Mouse Gene: Myl3

Allelic Composition	Genetic Background	Reference	Phenotypes
Myl3tm1a(EUCOMM)Hmgu/Myl3tm1a(EUCOMM)Hmgu Tg(Col2a1-cre)1Xya/0	involves: C57BL/6J * C57BL/6N	J:343166	View

Mouse Models

Human Disease Modeled: osteoarthritis
Associated Mouse Gene: Smad3

Allelic Composition	Genetic Background	Reference	Phenotypes
Smad3tm1Cxd/Smad3tm1Cxd	involves: 129S6/SvEvTac	J:68792	View

Mouse Models

Human Disease Modeled: osteoarthritis
Associated Mouse Gene: Tgfbr1

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Col2a1-cre/ERT2)1Dic/0 Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl	involves: 129 * C57BL/6	J:271724	View

Mouse Models

Human Disease Modeled: osteoarthritis
Associated Mouse Transgene: Tg(MT2A-TGFBR2)4Rser

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(MT2A-TGFBR2)4Rser/0	involves: C57BL/6 * DBA	J:44579	View

Mouse Models

Human Disease Modeled: osteoarthritis

Allelic Composition	Genetic Background	Reference	Phenotypes
Bgntm1Mfy/Y Fmodtm1Aol/Fmodtm1Aol	involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ	J:112779, J:117908	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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